AIDS in Africa / edited by Max Essex ... [and others].

Format:

Book

Contributor:

Essex, Myron.

Language:

English

Subjects (All):

AIDS (Disease)--Africa.

AIDS (Disease).

Africa.

Physical Description:

xx, 724 pages : illustrations ; 26 cm

Edition:

Second edition.

Place of Publication:

New York : Kluwer Academic/Plenum Publishers, [2002]

Summary:

This comprehensive reference book addresses the unique challenges facing many African nations as poor infrastructure and economics continue to obstruct access to advanced treatments and AIDS care training. While it takes into account the context of settings with limited resources, it also looks ahead to how many African nations are successfully increasing their capacity to serve those affected by HIV and AIDS. Information on how to best utilize existing resources and prioritize scaling-up of infrastructure is a critical aspect of this book for those working in HIV/AIDS-related fields in Africa.

Contents:

I Pathogenesis

1 Introduction: The Etiology of AIDS / Max Essex, Souleymane Mboup 1

2 The Molecular Virology of HIV-1 / Monty Montano, Carolyn Williamson 11

3 Immunopathogenesis of AIDS / Lynn Zijenah, David A. Katzenstein 34

4 Effect of Genetic Variation on HIV Transmission and Progression to AIDS / Cheryl A. Winkler, Stephen J. O'Brien 52

5 Biology of Human Immunodeficiency Virus Type 2 (HIV-2) / Phyllis J. Kanki, Jean-Louis Sankale, Souleymane Mboup 74

6 Simian Immunodeficiency Viruses and the Origin of HIVs / Ousmane M. Diop, Aissatou Gueye, Ahidjo Ayouba, Eric Nerrienet, Sylvie Corbet, Philippe Mauclere, Francois Simon, Francoise Barre-Sinoussi, Michaela C. Muller-Trutwin 104

II Detection and Monitoring of HIV Infection and Disease

7 Serodiagnosis of HIV Infection / Aissatou Gueye-Ndiaye 121

8 Molecular Diagnosis of HIV Infection / Boris Renjifo 138

9 Monitoring HIV-1 Subtype Distribution / Francis R. Barin, Coumba Toure-Kane, Jean-Christophe Plantier, Martine Peeters 158

10 Monitoring Viral Load / Phyllis J. Kanki, Indu Mani 173

11 Monitoring Immune Function / Gunnel Biberfeld, Eligius Lyamuya 185

III Epidemiology

12 The Epidemiology of HIV and AIDS / Peter Piot, Michael Bartos 200

13 Transmission of HIV / Sibylle Kristensen, Moses Sinkala, Sten H. Vermund 217

14 Role of Sexually Transmitted Diseases in HIV-Transmission / Saidi H. Kapiga, Iain W. Aitken 231

15 Mother-to-Child Transmission of HIV / Anne Willoughby 251

16 HIV-1 Subtypes and Recombinants / Boris Renjifo, Max Essex 263

17 Current Estimates and Projections for the Epidemic / Karen A. Stanecki, Neff Walker 281

IV Clinical Spectrum and Treatment of HIV-Related Diseases

18 Clinical Diagnosis of AIDS and HIV-Related Diseases / Churchill Lukwiya Onen 297

19 Antiretroviral Therapy in Resource-Limited Settings / Anthony Amoroso, Charles E. Davis, Robert R. Redfield 322

20 HIV-1 Drug Resistance / Mark A. Wainberg, Bluma G. Brenner 345

21 Opportunistic Infections / Robert Colebunders, Patrick K. Kayembe, Ann Marie Nelson 355

22 Tuberculosis / Renee Ridzon, Harriet Mayanga-Kizza 373

23 HIV Infection and Cancer / Robert Newton, Freddy Sitas, Martin Dedicoat, John L. Ziegler 386

24 Challenges and Opportunities for Nurses / Sheila D. Tlou 405

25 Home-Based Care / Quarraisha Abdool Karim, Samuel Kalibala, Elly T. Katabira, Zena A. Stein 411

26 Nutrition and HIV Infection / Annamaria K. Kiure, Gernard I. Msamanga, Wafaie W. Fawzi 419

27 Access to HIV and AIDS Care / Kirthana Ramanathan, Daniel Tarantola, Richard G. Marlink 436

V Pediatric HIV Infection and Disease

28 Diagnosis of Pediatric HIV Infection / Chewe Luo, Brian Coulter 458

29 Treatment of HIV in Children Using Antiretroviral Drugs / Gabriel M. Anabwani, Mark W. Kline 469

30 Pediatric Opportunistic Infections / Shahin Lockman, Kenneth McIntosh 480

VI Prevention of HIV Infection

31 Male Condoms and Circumcision / Roger L. Shapiro, Saidi H. Kapiga 498

32 Female Condoms and Microbicides / Eka Esu-Williams, Kelly Blanchard 506

33 Behavioral Change: Goals and Means / Poloko Kebaabetswe, Kathleen F. Norr 514

34 Voluntary Counseling and Testing / Elizabeth Marum, Carl H. Campbell, Katawa Msowoya, Augustine Barnaba, Beth Dillon 527

35 Prevention of Perinatal Transmission of HIV / Sophie Le Coeur, Marc Lallemant 539

36 Prevention of Breast Milk Transmission of HIV: Balancing the Benefits and the Risks / Ruth Nduati, Dorothy Mbori-Ngacha 560

37 Postexposure Prophylaxis for Occupational Exposure and Sexual Assault / Elisabeth Bouvet, Anne Laporte, Arnaud Tarantola 571

VII Vaccine Development

38 The Need for a Vaccine / Seth Berkley 584

39 HIV Vaccines: Design and Development / Tun-Hou Lee, Vlad Novitsky 594

40 HIV-1 Vaccine Testing, Trial Design, and Ethics / Peter B. Gilbert, Jose Esparza 612

VIII Impact and Response

41 Regional Variations in the African Epidemics / Max Essex, Souleymane Mboup 631

42 Human Rights and HIV/AIDS / Sofia Gruskin, Miriam Maluwa 641

43 Gender and HIV/AIDS / Sheila D. Tlou 654

44 The Orphan Crsis / Geoff Foster, Stefan Germann 664

45 The Economics of AIDS in Africa / Amar A. Hamoudi, Jeffrey D. Sachs 676

46 International Cooperation and Mobilization / Keith E. Hansen, Debrework Zewdie 695.

Notes:

Includes bibliographical references and index.

ISBN:

0306466996

OCLC:

49415667