3 options
Assessment of viral load and growth in children who are HIV-infected / Louise Mary Ash.
Holman Biotech Commons Thesis A819 2002
Available
LIBRA Diss. POPM2002.148
Available from offsite location
- Format:
- Book
- Manuscript
- Microformat
- Thesis/Dissertation
- Author/Creator:
- Ash, Louise Mary.
- Language:
- English
- Subjects (All):
- Penn dissertations--Nursing.
- Nursing--Penn dissertations.
- Nursing.
- Academic Dissertations as Topic.
- Medical Subjects:
- Nursing.
- Academic Dissertations as Topic.
- Local Subjects:
- Penn dissertations--Nursing.
- Nursing--Penn dissertations.
- Physical Description:
- ix, 143 pages ; 29 cm
- Production:
- 2002.
- Summary:
- Recent treatment and laboratory advances (e.g., viral load) have changed pediatric HIV disease from that of a rapidly fatal infection, to a chronic, though ultimately terminal disease. Now that children are living longer, the pervasive growth problems seen in this population need to be addressed. The purpose of this study was to examine the relationship among viral load, linear growth, and disease progression. Proposed hypotheses included: (1) High viral load will correlate with growth failure; (2) Improved viral load will correlate with improved linear growth; (3) Viral load and growth failure together will be more predictive of disease progression than either considered alone. A descriptive study guided by an epidemiologic framework was conducted using data from the Special Immunology pediatric database. The sample consisted of 97 children aged 3 to 12 years. Data including agent (viral load, disease progression), host (age, sex, birthweight, standing height, and weight), and environment (select maternal characteristics) variables obtained between January 1, 1996 and December 31, 2000 were abstracted from the registry. Results. High viral load was not related to growth failure or disease progression. However, children who demonstrated improved viral load also demonstrated improved linear growth. Finally, children who exhibited growth failure were less likely to exhibit disease progression.
- Notes:
- Supervisor: Terri H. Lipman.
- Thesis (Ph.D. in Nursing) -- University of Pennsylvania, 2002.
- Includes bibliographical references.
- Local Notes:
- University Microfilms order no.: 3054918.
- OCLC:
- 244971584
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.