Principles of cloning / edited by Jose Cibelli ... [and others].

Format:

Book

Contributor:

Cibelli, Jose B., 1963-

Clarence J. Marshall Memorial Library Fund.

Language:

English

Subjects (All):

Genetic engineering.

Cloning, Organism.

Cloning, Molecular.

Medical Subjects:

Cloning, Organism.

Cloning, Molecular.

Physical Description:

xxii, 531 pages : illustrations (some color) ; 29 cm

Place of Publication:

Amsterdam ; Boston : Academic Press, [2002]

Summary:

Principles of Cloning is the first comprehensive book on cloning since Dolly the sheep was cloned. The contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. The book spans from the earliest experiments in amphibians to the latest research on mammals as told by the scientists who performed this work. Covering the basic biological mechanisms of how cloning works, the book rounds out the discussion with a look at current and potential applications in basic biology, agriculture, biotechnology, and medicine. In addition to providing a clear and thorough understanding of cloning technology, the book also emphasizes the value of cloning in basic and applied research. Written in a clear, easy-to-comprehend style, this book is a great introduction to anyone interested in the science of cloning.

Contents:

1. Historical Perspective / Robert H. Foote 3

Part I Basic Biological Processes

2. Activation of Mammalian Oocytes / Rafael A. Fissore, Jeremy Smyth, Manabu Kurokawa, Philippe Collas 21

3. The Nucleus / Fyodor D. Urnov, Alan P. Wolffe 47

4. Nuclear Reprogramming: Biological and Technological Constraints / Kevin Eggan, Rudolf Jaenisch 85

5. Plasticity of Somatic Nucleus by Epigenetic Reprogramming via Cell Hybridization / Takashi Tada, Masako Tada, M. Azim Surani 99

6. Determinants of Pluripotency in Mammals / Michele Boiani, Hans R. Scholer 109

Part II Methods

7. Micromanipulation Techniques for Cloning / Raymond L. Page 155

8. Microinsemination and Nuclear Transfer with Male Germ Cells / Atsuo Ogura, Narumi Ogonuki, Kimiko Inoue 175

9. Development of Viable Mammalian Embryos in Vitro: Evolution of Sequential Media / David K. Gardner, Michelle Lane 187

10. Genetic and Phenotypic Similarity among Members of Mammalian Clonal Sets / George E. Seidel, Jr. 215

11. Genetic Modification and Cloning in Mammals / Patrick W. Dunne, Jorge A. Piedrahita 227

12. Pregnancy and Neonatal Care of Cloned Animals / Jonathan R. Hill, Pascale Chavatte-Palmer 247

13. Donor Cell Type and Cloning Efficiency in Mammals / Y. Tsunoda, Y. Kato 267

Part III Cloning by Species

14. Cloning of Amphibians / J. B. Gurdon, J. A. Byrne 281

15. Cloning of Fish / Yuko Wakamatsu, Kenjiro Ozato 287

16. Cloning of Mice / Teruhiko Wakayama, Anthony C. F. Perry 301

17. Cloning of Rabbits / Andras Dinnyes, X. Cindy Tian, Xiangzhong Yang 343

18. Nuclear Transfer in Swine / Randall S. Prather 367

19. Cloning of Cattle / Neal L. First, Zeki Beyhan, Jennifer D. Ambroggio 375

20. Cell Cycle Regulation in Cloning / Keith H. S. Campbell 391

Part IV Currently Sought after Species

21. Cloning of Rats / Philip Iannaccone, Michael Bader, Vasiliy Galat 403

Part V Nuclear Transfer in Primates

22. Cloning in Nonhuman Primates / Tanja Dominko, Calvin Simerly, Crista Martinovich, Gerald Schatten 419

Part VI Applications

23. Nuclear Transfer for Stem Cells / Alan Trounson 435

24. Current Research and Commercial Applications of Cloning Technology / Steven L. Stice 443

25. Transgenic Cloned Goats and the Production of Therapeutic Proteins / Esmail Behboodi, LiHow Chen, Margaret M. Destrempes, Harry M. Meade, Yann Echelard 459

Part VII Ethical and Legal Affairs

26. Ethical Implications of Cloning / Ronald M. Green 477

Final Remarks

27. Mammalian Cloning: Challenges for the Future / R. L. Gardner 497.

Notes:

Includes bibliographical references and indexes.

Local Notes:

Acquired for the Penn Libraries with assistance from the Clarence J. Marshall Memorial Library Fund.

ISBN:

012174597X

OCLC:

50679660