Combination treatment in autoimmune diseases / W.B. Harrison, B.A.C. Dijkmans, eds.

Format:

Book

Contributor:

Harrison, W. B., Dr.

Dijkmans, B. A. C.

Language:

English

Subjects (All):

Autoimmune diseases--Chemotherapy.

Autoimmune diseases.

Chemotherapy, Combination.

Autoimmune Diseases--drug therapy.

Drug Therapy, Combination.

Medical Subjects:

Autoimmune Diseases--drug therapy.

Drug Therapy, Combination.

Physical Description:

vi, 213 pages : illustrations ; 24 cm

Place of Publication:

Berlin ; New York : Springer-Verlag, [2002]

Summary:

This book consists of contributions from the most prominent experts in this field. In the first section the general principles of combination treatment are discussed, from rationale and methodology to benefits of risks in daily practice. The second section concerns specific diseases. It is striking that although there is so much experience with combining DMARDS in RA, for several other autoimmune diseases combination therapy has not yet been developed. Denton and Black, on the other hand, are able to add a refreshing new meaning to the term "combination therapy" in systemic sclerosis by pointing out the aetiologies beyond those caused by immunopathology, and dealing with combinations of therapy to address issues beyond immunotherapy. The last section is devoted to the future, and the editors hope to come back in 2010 with an issue which will look back and determine whether the predictions of Brooks, Moore, Huizinga and Breedveld have come true.

Contents:

Combination treatment in autoimmune diseases-Introduction / W.B. Harrison, B.A.C. Dijkmans 3

Combination therapy for autoimmune diseases: the rheumatoid arthritis model / N. Fathy, D.E. Furst 5

Methodology of combination trials / M. Boers 27

Regulatory aspects of evaluating combination treatments in autoimmune diseases / P. Kurki 35

New therapies in development for autoimmune diseases: their rationale for combination treatment / V. Strand 43

Combination therapy: the risks of infection and tumor induction / D.E. Yocum 63

II Disease specific section

Combination treatment in autoimmune diseases: Systemic lupus erythematosus / G. Moroni, O. Della Casa Alberighi, C. Ponticelli 75

Combination therapy in autoimmune disease: vasculitis / D. Carruthers, P. Bacon 91

Combination therapies for systemic sclerosis / C.P. Denton, C.M. Black 109

Therapy of Sjogren's syndrome / N.M. Moutsopoulos, H.M. Moutsopoulos 131

Spondylarthropathies: options for combination therapy / A.M. van Tubergen, R.B.M. Landewe, S. van der Linden 147

Combination therapy in rheumatoid arthritis / S. Binghman, P. Emery 165

III Futurology

What will treatment of autoimmune diseases entail in 2010? / T.W.J. Huizinga, F.C. Breedfeld 187

Stem cell transplantation for autoimmune diseases / J. Moore, P. Brooks 193.

Notes:

Includes bibliographical references.

ISBN:

3540430369

OCLC:

49874556