Genomes / edited by Terence A. Brown.

Format:

Book

Contributor:

Brown, T. A. (Terence A.)

Language:

English

Subjects (All):

Genomes.

Genome.

Medical Subjects:

Genome.

Physical Description:

xxvii, 572 pages : color illustrations, maps ; 29 cm

Edition:

Second edition.

Place of Publication:

New York : Wiley-Liss, [2002]

Summary:

Genomes 2 has been completely rewritten to take into account the changing demands of lecturers and their students: Part 1 has been completely reorganized and rewritten to provide an introduction to the subject for those studying molecular biology for the first time. Furthermore, there have been major pedagogical improvements to this edition: each chapter starts with a learning outcomes section which describes what the reader will learn and concludes with problems sets to aid understanding and also to help direct supplementary tutorial work.

The first edition of GENOMES was widely praised as the most up-to-date molecular biology book available. To continue this theme, Terry Brown has incorporated the huge changes in research over the last three years. As a consequence, the book starts by focusing on the draft human genome sequence and then leads into a survey of the physical and genetic organization of genomes in general. Our current understanding of the transcriptome and proteome is reviewed and an entirely new chapter on cloning techniques has been added.

Contents:

Part 1 Genomes, Transcriptomes and Proteomes 1

Chapter 1 The Human Genome 3

Chapter 2 Genome Anatomies 29

Chapter 3 Transcriptomes and Proteomes 69

Part 2 Studying Genomes 93

Chapter 4 Studying DNA 95

Chapter 5 Mapping Genomes 125

Chapter 6 Sequencing Genomes 163

Chapter 7 Understanding a Genome Sequence 187

Part 3 How Genomes Function 219

Chapter 8 Accessing the Genome 221

Chapter 9 Assembly of the Transcription Initiation Complex 239

Chapter 10 Synthesis and Processing of RNA 273

Chapter 11 Synthesis and Processing of the Proteome 313

Chapter 12 Regulation of Genome Activity 347

Part 4 How Genomes Replicate and Evolve 381

Chapter 13 Genome Replication 383

Chapter 14 Mutation, Repair and Recombination 417

Chapter 15 How Genomes Evolve 459

Chapter 16 Molecular Phylogenetics 483.

Notes:

Rev. ed. of: Genomes / T.A. Brown. 1999.

Includes bibliographical references and index.

ISBN:

0471250465

OCLC:

49278577