Assessing and modifying the vulnerable atherosclerotic plaque / edited by Valentin Fuster with assistance from William Insull, Jr.

Format:

Book

Contributor:

Fuster, Valentin.

Series:

American Heart Association monograph series

Language:

English

Subjects (All):

Atherosclerotic plaque.

Atherosclerosis.

Arteriosclerosis--diagnosis.

Arteriosclerosis--therapy.

Diagnostic Imaging--methods.

Medical Subjects:

Arteriosclerosis--diagnosis.

Arteriosclerosis--therapy.

Diagnostic Imaging--methods.

Physical Description:

xv, 379 pages : illustrations (some color) ; 24 cm.

Place of Publication:

Armonk, NY : Futura Pub. Co., [2002]

Summary:

Edited by the former Chairman of the American Heart Association's Committee on Vascular Lesions, this monograph is a valuable multidisciplinary resource, written by experts in the fields of mechanical and electrical engineering, pathology, neurology, imaging, clinical and vascular biology, physics, radiology and surgery. The book's nineteen chapters and five Panel Discussions provides a wealth of information on the identification and treatment of atherosclerotic plaques, including the latest diagnostic applications of numerous imaging techniques, the reasons for selecting a particular method, and what can be learned from the imaging results. Important insights into the structural and cellular components of vulnerable plaque are presented, as well as an examination of factors/activities that trigger thrombosis.

Contents:

Chapter 1. Evolving Concepts of Atherothrombosis / Valentin Fuster, MD, PhD, Roberto Corti, MD 1

Chapter 2. Cerebrovascular Diseases: Pathophysiology and Management / Debabrata Mukherjee, MD, Jay S. Yadav, MD 29

Chapter 3. Aortic Arch Vulnerable Plaques: Update / Pierre Amarenco, MD, Ariel Cohen, MD, PhD 57

Chapter 4. The Vulnerable Atherosclerotic Plaque in Peripheral Vascular Disease / Michael L. Marin, MD, Larry H. Hollier, MD, Valentin Fuster, MD, PhD, Jeffrey Goldman, MD 85

Panel Discussion I. Overview of Pathology: Clinical Correlations of Atherosclerosis 101

Chapter 5. Thermography: A Novel Approach for Identification of Plaques at Risk of Rupture and/or Thrombosis / Mohammad Madjid, MD, Morteza Naghavi, MD, James T. Willerson, MD, Ward Casscells, MD 107

Chapter 6. Intravascular Ultrasound and Plaque Vulnerability: Evidence of a Systemic Disease Process / Paul Schoenhagen, MD, Steven E. Nissen, MD, FACC 129

Chapter 7. Intracoronary Angioscopy to Detect Vulnerable Plaques: A Technique Whose Time Has Come? / Sergio Waxman, MD 143

Chapter 8. Electron Beam Computed Tomography in Assessing the Vulnerable Atherosclerotic Plaque / Robert A. O'Rourke, MD 151

Chapter 9. Multirow-Detector Helical Computed Tomography / Christoph R. Becker, MD, Uwe J. Schoepf, MD, Maximilian F. Reiser, MD 167

Panel Discussion IIA. Overview of Imaging: Coronary Atherosclerosis 175

Chapter 10. Imaging of the High-Risk Plaque Using Magnetic Resonance Imaging / Zahi A. Fayad, PhD, Valentin Fuster, MD, PhD 181

Chapter 11. Cardiovascular Imaging with Optical Coherence Tomography / Mark E. Brezinski, MD, PhD, James Fujimoto, PhD 201

Panel Discussion IIB. Overview of Imaging: Atherosclerotic Regions and Imaging Modalities 219

Chapter 12. Plaque Instability and Remodeling: Mechanisms and Possible Misconceptions / Trine-Line Korsholm, MS, Gerard Pasterkamp, MD, PhD, MSc, Erling Falk, MD, PhD 225

Chapter 13. Structural and Cellular Components of the Vulnerable Plaque: Extracellular Matrix / Renu Virmani, MD, Frank D. Kolodgie, PhD, Allen P. Burke, MD, Andrew Farb, MD, Thomas N. Wight, PhD 241

Chapter 14. Structural and Cellular Components of the Vulnerable Plaque: Inflammatory Cells / Allard C. van der Wal, MD, PhD, Mischa A. Houtkamp, MSc, Onno J. de Boer, PhD, Anton E. Becker, MD, PhD 251

Panel Discussion III. Structural and Cellular Components of the Vulnerable Atherosclerotic Plaque 269

Chapter 15. Stress and Strain: Biomechanical Guides for Imaging Plaque Stability / Hayden Huang, DSc, Richard T. Lee, MD 277

Chapter 16. Endothelium, Flow, and Atherothrombosis / Roberto Corti, MD, Lina Badimon, PhD, Valentin Fuster, MD, PhD, Juan Jose Badimon, PhD 287

Chapter 17. Activities that Trigger Plaque Disruption / Jagmeet P. Singh, MD, DM, PhD, James Januzzi, MD, James E. Muller, MD 307

Panel Discussion IV. Mechanical Forces in Plaque Disruption 327

Chapter 18. Matrix Metalloproteinases and Their Inhibitors / Uwe Schonbeck, PhD, Peter Libby, MD 335

Chapter 19. Calcium Deposition in Vulnerable Atherosclerotic Plaques: Pathophysiologic Mechanisms and Potential Implications in the Acute Coronary Syndromes / Pedro R. Moreno, MD 347

Panel Discussion V. Regulation of Functional Components of the Vulnerable Plaque 365.

Notes:

Includes bibliographical references and index.

ISBN:

0879934859

OCLC:

48434884