Clinical chemistry : laboratory management and clinical correlations / editor, Kent Lewandrowski.

Format:

Book

Contributor:

Lewandrowski, Kent.

Rosengarten Family Fund.

Language:

English

Subjects (All):

Clinical chemistry.

Clinical chemistry laboratories--Management.

Clinical chemistry laboratories.

Chemistry, Clinical--organization & administration.

Laboratories--organization & administration.

Management.

Medical Subjects:

Chemistry, Clinical--organization & administration.

Laboratories--organization & administration.

Physical Description:

xiii, 952 pages : illustrations ; 29 cm

Place of Publication:

Philadelphia : Lippincott Williams & Wilkins, [2002]

Summary:

A modern text that combines the fundamentals of methodology with key elements of interpretation, this book blends business and management issues, analytical principles, and clinical material for practicing pathologists, residents, fellows, and laboratiorians. The text is organized into three major sections: laboratory management, instrumentation and methods, and analysis and clinical correlation. The first section addresses issues essential for running a profitable laboratory; modern techniques and instrumentation are examined in the second section; and the analysis and clinical correlation section provides the reader with numerous diagnostic algorithms that illustrate common work-ups and problems. In addition, case studies selectively illuminate specific clinical issues.

Contents:

Section I Laboratory Management 1

1. Overview of Laboratory Management: An Introduction and Perspective / Kent Lewandrowski 3

2. Accreditation and Regulation in the Clinical Laboratory / Donna H. MacMillan 13

3. Human Resources Management / Diane Cosmidis, Elizabeth Taylor, Kent Lewandrowski 25

4. Laboratory Safety: An Overview / J. Keith Joung, Kent Lewandrowski 40

5. The Laboratory Manager: Role in Compliance, Organizational Structure, and Financial Management / Lawrence J. Crolla, Paul W. Stiffler, Sheryl Vacca, Stephanie M. McNear 51

6. Budget Management and Benchmarking / William M. Hynes, Dion S. Buchner 64

7. Cost Accounting in the Clinical Laboratory / Dion S. Buchner, William M. Hynes 71

8. Quality Control / Quality Assurance / Frank H. Wians, Jr., David D. Koch, Amy Haara 81

9. Diagnostic Accuracy of Laboratory Tests and the Establishment of Reference Ranges / Eleftherios C. Vamvakas 107

10. Method Evaluation and Technology Assessment / Pennell C. Painter 122

11. Operations Analysis, Reengineering, and Process Improvement / Peter R. Ciment 152

12. Reimbursement for Laboratory Services / Donna H. MacMillan 165

13. Point-of-Care Testing / James H. Nichols 175

14. Specimen Transport, Logistics, and Processing / Antony O. Okorodudu, M. Tarek Elghetany 195

15. Integrated Automation in the Clinical Laboratory / Lokinendi V. Rao, Antony O. Okorodudu 205

16. Development of Laboratory Instrument Platforms / Roy Marcus 212

17. Assay Development and the Role of the FDA / Alan E. Burkhardt 227

Part 1. Overview of Laboratory Information Systems: Computing Knowledge for the Laboratorian / H. Dominic Covvey, Joseph J. Stumpf 237

Part 2. Management and the Laboratory Information System / H. Dominic Covvey, Joseph J. Stumpf 284

19. Role of Laboratories in Integrated Delivery Networks / William M. Hynes 310

20. The Commercial Reference Laboratory / Geraldine M. Beyer, Kent Lewandrowski 317

21. Management of Test Utilization / M. Tarek Elghetany, Anthony O. Okorodudu 323

22. Acute Care and STAT Laboratory Testing / Ellis Jacobs 331

23. The Role of the Diagnostics Industry in the Clinical Chemistry Laboratory / Michael D. Hoyt 347

Section II Instrumentation and methods / Section Editor: Darryl Erik Palmer-Toy 357

24. General Laboratory Techniques, Units of Measurement, and a Table of Representative Normal Reference Values / Kent Lewandrowski, Alexander Kratz 359

25. Contemporary Instruments in the Clinical Laboratory: A Brief Overview / Elizabeth Lee-Lewandrowski, Kent Lewandrowski 375

26. Photometric Methods, Fluorometry, Atomic Absorption, Nephelometry, and Turbidimetry / Steven M. Faynor, William C. Bastan 385

27. Mass Spectrometry / Peter E. Leopold, Darryl Erik Palmer-Toy 403

28. An Introduction to Clinical Laboratory Immunodiagnostics: A Perspective from the Diagnostics Industry / George Parsons 413

29. Immunoassay and Immunoassay Analyzers: A Perspective from the Clinical Laboratory / Bode B. Adesoji, John R. Petersen 429

30. Chromatography and Capillary Electrophoresis: Principles and Practical Consideration / Zak K. Shihabi 439

31. Electrochemistry / Paul D'Orazio 453

32. Electrophoresis / Rita Ellerbrook 468

33. Measurement of Osmolality and Specific Gravity / Kent Lewandrowski 481

34. Molecular Diagnostics: Methods and Applications / James Versalovic 484

35. Clinical Enzymology / Kelly Y. Chun 500

36. Radioimmunoassay / Patrick M. Sluss 521

Section III Analysis and Clinical Correlations 529

37. The Plasma Proteins / Alexander Kratz, Elizabeth Lee-Lewandrowski, Kent Lewandrowski 531

38. Glucose and Carbohydrates / Kenneth Emancipator 561

39. Lipids, Lipoproteins, and Cardiovascular Risk Assessment / Gyorgy Abel, Michael Laposata 575

40. Laboratory Diagnosis of Disorders of the Thyroid Gland / Yash P. Agrawal, Kent Lewandrowski 592

41. Laboratory Evaluation of Pituitary Disorders, Adrenal Cortex and Medulla, and Selected Neuroendocrine Tumors / Yash P. Agrawal, Kent Lewandrowski 606

42. Reproductive Endocrinology / Frances Hayes, Sabrina Gill, Patrick M. Sluss 625

43. Acid-Base and Electrolyte Disorders / Kent Lewandrowski 639

44. Respiration and the Evaluation of Hypoxemia, Hypercapnia, and Related Disorders / Kent Lewandrowski, Michael Pins, Robert W. Burnett 659

45. Cardiac Markers / Alan H.B. Wu 671

46. Renal Function and Nitrogen Metabolites / Zbigniew M. Szczepiorkowski, Kent Lewandrowski 689

47. Calcium, Magnesium, and Phosphate / John G. Toffaletti 710

48. Evaluation of Hepatic Function and Disorders of the Liver / David R. Coon, Kent Lewandrowski 725

49. Inborn Errors of Metabolism / Tina M. Cowan, Miriam G. Blitzer 750

50. Toxicology Testing in the Clinical Laboratory / Jane Yang 767

51. Therapeutic Drug Monitoring / Jane Yang, Kent Lewandrowski 784

52. Trace Elements, Vitamins, and Nutrition / Jane Yang, Kent Lewandrowski 796

53. Disorders of Porphyrin Synthesis and of Iron Metabolism / Gyorgy Abel, Anil Parwani 825

54. Human Chorionic Gonadrotropin and Clinical Laboratory Testing in the Diagnosis and Management of Pregnancy / Alexander Kratz, Jane Yang, Kent Lewandrowski 841

55. Clinical Chemistry of Urine, Pleural Effusions, and Ascites / William Clarke, Darryl Erik Palmer-Toy 849

56. Tumor Markers / Morton K. Schwartz 865

57. Cerebrospinal Fluid / Philip J. Boyer, Zachary Simmons, Thomas P. Nifong 877

58. Coagulation / Elizabeth M. Van Cott 892

59. Disorders of Bone Chemistry and Clinical Correlations / Kent Lewandrowski 912

60. Laboratory Evaluation of Pancreatic Disorders, Malabsorption, and Diseases of the Gastrointestinal System / Kent Lewandrowski, Darryl Erik Palmer-Toy, James Versalovic 918.

Notes:

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Rosengarten Family Fund.

ISBN:

0683300857

OCLC:

48046423