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The tumour microenvironment : causes and consequences of hypoxia and acidity / [editors, Jamie A. Goode and Derek J. Chadwick].
Holman Biotech Commons R850.A2 N69 v.240 2001
Available
- Format:
- Book
- Conference/Event
- Conference Name:
- Symposium on the Tumour Microenvironment: Causes and Consequences of Hypoxia and Acidity (2000 : London, England)
- Series:
- Novartis Foundation symposium ; 240.
- Novartis Foundation symposium ; 240
- Language:
- English
- Subjects (All):
- Carcinogenesis--Congresses.
- Carcinogenesis.
- Tumors--Metabolism--Congresses.
- Tumors.
- Acidosis--Congresses.
- Acidosis.
- Anoxemia--Congresses.
- Anoxemia.
- Cancer cells--Regulation--Congresses.
- Cancer cells.
- Cancer invasiveness--Congresses.
- Cancer invasiveness.
- Metastasis--Congresses.
- Metastasis.
- Neoplasms--physiopathology.
- Metabolism.
- Neoplasms--metabolism.
- Cell Hypoxia--physiology.
- Hydrogen-Ion Concentration.
- Neoplasm Invasiveness--physiopathology.
- Neoplasm Metastasis--physiopathology.
- Medical Subjects:
- Neoplasms--physiopathology.
- Neoplasms--metabolism.
- Cell Hypoxia--physiology.
- Hydrogen-Ion Concentration.
- Neoplasm Invasiveness--physiopathology.
- Neoplasm Metastasis--physiopathology.
- Genre:
- Conference papers and proceedings.
- Physical Description:
- ix, 303 pages : illustrations (some color) ; 24 cm.
- Place of Publication:
- Chichester ; New York : Wiley, 2001.
- Summary:
- Several fundamentally important questions form the basis for this book. What are the relationships between tumour formation and tumour pH? What are the effects of tumour pH and hypoxia on carcinogenesis or tumorigenesis? What are the therapeutic consequences of tumour pH?
- It is hypothesised that low extracellular pH is not only an important consequence of tumour growth but may also promote further tumorigenic transformation. Furthermore, "in vitro" studies suggest that low pH strongly affects the efficacy of chemo- and radiotherapy. Better understanding of the influence of pH on tumour growth, coupled with manipulation of the pH of the tumour microenvironment, may lead to the development of more effective therapies.
- Notes:
- "Symposium on the Tumour Microenvironment: Causes and Consequences of Hypoxia and Acidity, held at the Novartis Foundation, London, October 10-12, 2000"--Contents p.
- Includes bibliographical references and index.
- ISBN:
- 0471499595
- OCLC:
- 47289367
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