Hormone resistance and hypersensitivity states / editors, George P. Chrousos, Jerrold M. Olefsky, Ellis Samols.

Format:

Book

Contributor:

Chrousos, George P.

Olefsky, Jerrold M.

Samols, Ellis.

Series:

Modern endocrinology

Language:

English

Subjects (All):

Hormone resistance.

Hormones--metabolism.

Hormone Antagonists--therapeutic use.

Hypersensitivity.

Medical Subjects:

Hormones--metabolism.

Hormone Antagonists--therapeutic use.

Hypersensitivity.

Physical Description:

xvi, 542 pages : illustrations ; 26 cm.

Place of Publication:

Philadelphia : Lippincott Williams & Wilkins, [2002]

Summary:

Physiologic adaptations and pathologic states that result from changes of target tissue sensitivity to hormones are vital concerns in endocrinology. Part of the Modern Endocrinology Series, this text features an overview of the human hormone resistance and hypersensitivity syndromes due to pre-receptor, receptor and postreceptor abnormalities. Focuses on the pivotal study of the etiology of common conditions, such as obesity and essential hypertension, in chapters written by experts who have performed primary research in hormone action.

Contents:

1. History of Hormone Resistance / Ellis Samols 1

2. Biorhythms, Pulsatility, and Hormone Resistance / Johannes D. Veldhuis 11

3. Counterregulatory Factors / Philip E. Cryer 45

4. Prereceptor Hormone Resistance / Phillip Gorden 53

5. The Role of Cell Surface Receptors in Hormone and Growth Factor Signaling: An Overview / Derek L. Le Roith, Andrew A. Butler, Vicky A. Blakesley 65

6. Tyrosine Kinases / Simeon I. Taylor 89

7. Resistance to Somatostatin Analogue Therapy / Leo J. Hofland, W.W. de Herder, Steven W.J. Lamberts 103

8. Mutations of the Insulin Receptor / Jonathan Whittaker 119

9. Mechanisms of Insulin Resistance in Obesity / David E. Kelley 133

10. Endocrine and Pharmacologic Causes of Insulin Resistance / Rosalind D. Leaming, Melvin J. Prince 143

11. Obesity and Hormone Resistance: Comparing Apples with Pears / Alan N. Peiris 167

12. Insulin Resistance in Patients with IDDM / Hannele Yki-Jarvinen 175

13. Leptin Resistance and Obesity / Michael W. Schwartz, Denis G. Baskin 187

14. Molecular Mechanisms for Resistance to Thyroid Hormone / Paul M. Yen 205

15. The Syndrome of Resistance to Thyrotropin (TSH) / Nicholas J. Sarlis, Paul M. Yen 229

16. Somatic Mutations: Hot Thyroid Nodules, Clonal Adenoma / Victor J. Bernet, Kenneth D. Burman 239

17. Growth Hormone Resistance (Laron Syndrome) / Zvi Laron 251

18. The PTH/PTHrP Receptor in Human Diseases / Percy H. Carter, Ernestina Schipani 269

19. Ca[superscript 2+]-Sensing Receptor Abnormalities / Maria Veronica Mericq, Jeffrey Baron 289

20. Hereditary Vitamin D

Resistant Rickets / Julia Barsony 301

21. Nephrogenic Diabetes Insipidus / Daniel G. Bichet 315

22. Hormone Resistance in Fetus and Mother During Pregnancy / Robert E. Ratner, Maureen D. Passaro 331

23. Steroidogenic Factor 1 (SF-1) / Keith L. Parker 345

24. Steroidogenic Acute Regulatory Protein (StAR): The Regulator of the Rapid Steroidogenic Response to Trophic Stimulation / Staci E. Pollack, Futoshi Arakane, Caleb B. Kallen, Hidemichi Watari, Marianthi Kiriakidou, Jerome F. Strauss III 353

25. X-linked Adrenal Hypoplasia Congenita (AHC): A DAX1 Deficiency Disorder / Eric Vilain, Wei-Wen Guo, Megha Patel, Edward R.B. McCabe 363

26. Glucocorticoid Resistance and Hypersensitivity States / Denis P. Franchimont, Alessandra Vottero, Tomoshige Kino, George P. Chrousos 373

27. Pseudohypoaldosteronism: Sporadic and Familial Mineralocortoid Resistance / Keiko Arai, Tamotsu Shibasaki, George P. Chrousos 389

28. Glucocorticoid Modulation of Neural and Endocrine Control of Blood Pressure: Alterations in the Sensitivity of Vasopressor Systems / Robert Fraser, Guthrie Blackhurst 399

29. Androgen Insensitivity Syndrome / Claude J. Migeon, Amy B. Wisniewski, Terry R. Brown 409

30. Familial Male Precocious Puberty / Ellen Werber Leschek, Gordon B. Cutler 441

31. Adrenocorticotropic Hormone (ACTH) Resistance

The Triple A Syndrome / Constantine Tsigos 447

32. Estrogen Resistance / Eric P. Smith 455

33. Aromatase Deficiency / Serdar E. Bulun, Evan R. Simpson 467

34. Luteinizing Hormone and Follicle-Stimulating Hormone Receptor-Mediated Resistance and Autonomy States / Ana C. Latronico, George P. Chrousos 477

35. Glucocorticoid Hypersensitivity / Sayomi Iida, Hiroshi Fujii, Kaname Moriwaki 485

36. Adrenocorticotropic Hormone (ACTH) Hypersensitivity Syndrome: A Preliminary Study / Yukitaka Miyachi, Naoki Hiroi, Fumiatu Yakushiji, Masako Shimojo, Minako Matumoto, Hana Matoba, Hajime Uesiba, Kumiko Tuboi 491

37. Aromatase Excess: In Vitro and In Vivo Evidence of P-450arom Overactivity and Associated Clinical Syndromes / Constantine A. Stratakis 499

38. Future Perspectives / Ellis Samols 511.

Notes:

Includes bibliographical references and index.

ISBN:

0781714974

OCLC:

47965066