Introduction to proteomics : tools for the new biology / by Daniel C. Liebler ; foreword by John R. Yates, III.

Format:

Book

Author/Creator:

Liebler, Daniel C.

Contributor:

Rudolph G. Schmieder Fund.

Language:

English

Subjects (All):

Proteins--Research--Methodology.

Proteins.

Proteome--genetics.

Genome.

Protein Conformation.

Proteome--analysis.

Sequence Analysis--methods.

Proteins--Research.

Medical Subjects:

Proteome--genetics.

Genome.

Protein Conformation.

Proteome--analysis.

Sequence Analysis--methods.

Physical Description:

ix, 198 pages : illustrations (some color) ; 21 cm

Other Title:

Proteomics

Place of Publication:

Totowa, NJ : Humana Press, [2002]

Summary:

Daniel C. Liebler masterfully introduces the science of proteomics by spelling out the basics of how one analyzes proteins and proteomes, and just how these approaches are then employed to investigate their roles in living systems. He explains the key concepts of proteomics, how the analytical instrumentation works, what data mining and other software tools do, and how these tools can be integrated to study proteomes. Also discussed are how protein and peptide separation techniques are applied in proteomics, how mass spectrometry is used to identify proteins, and how data analysis software enables protein identification and the mapping of modifications. In addition, there are proteomic approaches for analyzing differential protein expression, characterizing proteomic diversity, and dissecting protein -- protein interactions and networks.

Notes:

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Rudolph G. Schmieder Fund.

ISBN:

0896039919

OCLC:

48046062