Manual of clinical laboratory immunology / editors, Noel R. Rose, Robert G. Hamilton, Barbara Detrick.

Format:

Book

Contributor:

Rose, Noel R.

Hamilton, Robert G.

Detrick, Barbara.

Language:

English

Subjects (All):

Immunodiagnosis--Handbooks, manuals, etc.

Immunodiagnosis.

Immunology--Handbooks, manuals, etc.

Immunology.

Immunologic Techniques.

Immunologic Tests--methods.

Medical Subjects:

Immunologic Techniques.

Immunologic Tests--methods.

Genre:

Handbooks and manuals.

Laboratory manuals.

Physical Description:

xxv, 1322 pages : illustrations (some color) ; 29 cm

Edition:

Sixth edition.

Place of Publication:

Washington, D.C. : ASM Press, [2002]

Summary:

Featuring the latest on standard and cutting-edge immunological tests and procedures in clinical laboratory immunology, the much-anticipated sixth edition of the Manual of Clinical Laboratory Immunology (MCLI) reflects the continued evolution of clinical immunology.

Considered the "bible" of the clinical immunology laboratory, MCLI6 provides an up-to-date description of the methods used in the clinical laboratory for diagnosis and monitoring of immunemediated and autoimmune diseases, transplantation rejection, and cancer. The best features of earlier editions have remained in this update, including a step-by-step interpretive approach to methodology, with emphasis on the practical issues and pitfalls in performing laboratory procedures, the appropriate indication, and the interpretation of results.

Throrughly indexed and fully illustrated, this much-heralded reference has been called "a clear reflection of the practice of clinical laboratory immunology" (Current Microbiology).

Contents:

Section A General Methods: Antibody-Based and Molecular / Volume Editor: Robert G. Hamilton, Section Editor: David E. Normansell 3

2 Antibody-Based Methods / A. Betts Carpenter 6

3 Introduction to Molecular Methodology / Raymond P. Podzorski 26

4 Specimen Collection and Handling / David E. Normansell 49

Section B Immunoglobulin Methods / Volume Editor: Robert G. Hamilton, Section Editor: Robert A. Kyle 51

6 Immunoglobulin Genes / Thomas J. Kipps 54

7 Clinical Indications and Applications of Electrophoresis and Immunofixation / Robert A. Kyle, Jerry A. Katzmann, John A. Lust, Angela Dispenzieri 66

8 Immunochemical Characterization of Immunoglobulins / Robert A. Kyle, Jerry A. Katzmann, John A. Lust, Angela Dispenzieri 71

9 Immunoglobulin Quantification / David F. Keren 92

10 Cryoglobulins, Cryofibrinogenemia, and Pyroglobulins / Peter D. Gorevic, Dennis Galanakis 97

Section C Complement / Volume Editor: Robert G. Hamilton, Section Editor: Patricia C. Giclas 107

12 Choosing Complement Tests: Differentiating between Hereditary and Acquired Deficiency / Patricia C. Giclas 111

13 Molecular Genetic Analyses of Human Complement Components C4A and C4B / C. Yung Yu, Carol A. Blanchong, Erwin K. Chung, Kristi L. Rupert, Yan Yang, Zhenyu Yang, Bi Zhou, Joann M. Moulds 117

Section D Flow Cytometric Analysis / Volume Editor: Barbara Detrick, Section Editor: Michael J. Borowitz 133

15 Immunophenotyping of Lymphocytes by Flow Cytometry / Janet K. A. Nicholson 137

16 Immunophenotyping of Leukemia and Lymphoma by Flow Cytometry / Brent Lee Wood, Pamela G. Kidd 148

17 Functional Assays by Flow Cytometry / J. Paul Robinson, Wayne O. Carter, Padma K. Narayanan 160

18 DNA Content Flow Cytometry / T. Vincent Shankey, Peter S. Rabinovitch 171

19 Standardized Flow Cytometry Assays for Enumerating Hematopoietic Stem Progenitor Cells / D. Robert Sutherland, Michael Kenney, Ian Chin-Yee 185

20 Multiplexed Bead Assay in Flow Cytometry: Flow Cytometry-Based Suspension Array Technology / Francis F. Mandy 197

Section E Cellular Immunology Assays / Volume Editor: Barbara Detrick, Section Editor: Steven D. Douglas 209

22 Delayed-Type Hypersensitivity Skin Testing / Jintanat Ananworanich, William T. Shearer 212

23 Cryopreservation of Peripheral Blood Mononuclear Cells / Adriana Weinberg 220

24 T-Lymphocyte Activation and Cell Signaling / Stephen P. Perfetto, Jeffrey Currier, Deborah L. Birx 224

25 Methods for Detection of Antigen-Specific CD8[superscript +] T Cells and Assessment of Their Function / Douglas F. Nixon, Graham S. Ogg 238

26 Evaluation of the T-Cell Receptor Repertoire / Vivek Chitnis, Savita Pahwa 244

27 Molecular Diagnosis of Chronic Granulomatous Disease / Paul G. Heyworth, John T. Curnutte, Andrew R. Cross 256

28 Evaluation of Phagocytic Cell Function / Maurice R. G. O'Gorman 265

29 Flow Cytometric Detection and Quantification of Apoptotic Cells / Thomas W. McCloskey, Savita Pahwa 274

30 Non-Flow Cytometry-Based Cell Enumeration Systems / Maurice R. G. O'Gorman 284

31 Quantification of Recent Thymic Emigrants: T-Cell-Receptor Excision Circles / Paul Krogstad 291

32 Measurement of NK-Cell Activity in Humans / Theresa L. Whiteside 296

33 Cellular Immune Assays for Evaluation of Vaccine Efficacy in Developing Countries / Josephine H. Cox, Mark deSouza, Silvia Ratto-Kim, Guido Ferrari, Kent J. Weinhold, Deborah L. Birx 301

Section F Cytokines, Chemokines, and Adhesion Molecules / Volume Editor: Barbara Detrick, Section Editor: John J. Hooks 318

35 Protein Analysis and Bioassays of Cytokines and Cytokine Receptors / Daniel G. Remick 320

36 Flow Cytometric Analysis of Cytokines / Holden T. Maecker, Louis J. Picker, Vernon C. Maino 338

37 Molecular Analysis of Cytokines and Cytokine Receptors / Niels Kruse, Peter Rieckmann 347

38 Chemokine and Chemokine Receptor Analysis / Mark C. Poznansky, David T. Scadden, Andrew D. Luster 357

39 Cell Adhesion Molecules: Potential Therapeutic and Diagnostic Implications / Shaker A. Mousa 368

Section G Immunohistology and Immunopathology / Volume Editor: Noel R. Rose, Section Editors: Russell H. Tomar and Norman Pettigrew 378

41 Immunohistochemistry

Principles and Advances / Patrick C. Roche, Eric D. Hsi 380

42 Immunohistochemistry: Diagnostic and Prognostic Applications in Tumor Diagnosis / Raymond B. Nagle, Katherine M. Scott 387

43 Immunofluorescence Methods in the Diagnosis of Skin and Renal Disease / A. Bernard Collins, Robert B. Colvin, Hossein C. Nousari, Grant J. Anhalt 393

Part II Immunologic Diagnosis and Monitoring of Disease 403

Section H Infectious Diseases Caused by Bacteria, Mycoplasmas, Chlamydiae, and Rickettsiae / Volume Editor: Noel R. Rose, Section Editor: James D. Folds 405

45 Immune Response to Streptococcal Antigens: Diagnostic Methods / Elia M. Ayoub, Elaine Harden 409

46 Haemophilus influenzae Type b, Neisseria meningitidis, Streptococcus pneumoniae, and Corynebacterium diphtheriae Vaccines / George M. Carlone, Bradley A. Perkins, Tanja Popovic, Nancy Rosenstein, Sandra Romero-Steiner 418

47 Clostridium tetani: Immune Response and Diagnostic Methods / Martha L. Lepow, Patricia A. Hughes 432

48 Immunologic Methods for Diagnosis of Infections by Gram-Negative Cocci / Wendell D. Zollinger, John Boslego 435

49 Immunologic Methods for Diagnosis of Infections Caused by Diarrheagenic Members of the Families Enterobacteriaceae and Vibrionaceae / Genevieve A. Losonsky, Myron M. Levine 447

50 Serodiagnosis of Helicobacter pylori Infection and Eradication / Bruce E. Dunn 462

51 Detection of Antibodies to Legionella spp. / Paul H. Edelstein 468

52 Immunologic Methods for Diagnosis of Spirochetal Diseases / Victoria Pope, Sandra L. Bragg, Martin E. Schriefer, Sandra A. Larsen 477

53 Lyme Disease: Serodiagnosis of Borrelia burgdorferi Sensu Lato Infection / Russell C. Johnson, Barbara J. B. Johnson 494

54 Immunological Tests in Tuberculosis and Leprosy / Graham H. Bothamley 502

55 Nocardiae and Agents of Actinomycosis / Blaine L. Beaman 511

56 Mycoplasma Infection: Immunologic and Molecular Biologic Diagnostic Techniques / Stephen G. Baum 516

57 Chlamydiae / Julius Schachter 522

58 Immunoserology of the Rickettsiales, Bartonella, and Coxiella / Karim E. Hechemy, Yasuko Rikihisa 528

Section I Mycotic and Parasitic Diseases / Volume Editor: Robert G. Hamilton, Section Editor: Thomas Nutman 543

60 Clinical Immunoparasitology / Marianna Wilson, Peter M. Schantz, Thomas Nutman, Victor C. W. Tsang 547

61 Clinical Immunomycology / Errol Reiss, Leo Kaufman, Joseph A. Kovacs, Mark D. Lindsley 559

Section J Viral Diseases / Volume Editor: Barbara Detrick, Section Editor: Steven Specter 585

63 Rapid Viral Diagnosis / Marie Louise Landry 588

64 Antibody-Enhanced Detection of Viruses in Cell Cultures / Thomas F. Smith 598

65 Herpes Simplex Virus / John A. Stewart, D. Scott Schmid 605

66 Varicella-Zoster Virus / D. Scott Schmid, Vladimir Loparev 611

67 Epstein-Barr Virus / Hal B. Jenson, Yasmin Ench 615

68 Cytomegalovirus / Kirsten St. George, Charies R. Rinaldo, Jr. 627

69 Human Herpesvirus 6, 7, and 8 / Richard L. Hodinka 635

70 Papovaviruses / Keerti V. Shah 646

71 Adenoviruses / Leta K. Crawford-Miksza, David P. Schnurr 652

72 Parvovirus B19 / Yuory V. Karetnyi, Stanley J. Naides 659

73 Influenza Viruses / Thedi Ziegler, Nancy J. Cox 666

74 Respiratory Syncytial Virus and the Parainfluenza Viruses / Maurice A. Mufson 672

75 Measles and Mumps / Diane S. Leland 682

76 Rubella Virus / James B. Mahony, Max A. Chernesky 687

77 Enteroviruses / David P. Schnurr 693

78 Viral Hepatitis / Mauro Bendinelli, Mauro Pistello, Giulia Freer, Marialinda Vatteroni, Fabrizio Maggi 696

79 Enzyme Immunoassays for Detection of Rotavirus Antigen and Antibody / Ningguo Feng, Suzanne M. Matsui 718

80 Arboviruses / John T. Roehrig 727

81 Hantaviruses / Stephen A. Young 736

82 Rabies Virus / D.

Craig Hooper 742

83 Human T-Cell Lymphotropic Virus Types I and II / Susan B. Nyland, Chuanhai Cao, Kenneth E. Ugen 749

Section K Human Immunodeficiency Virus / Volume Editor: Barbara Detrick, Section Editor: H. Clifford Lane 755

85 Immunologic Evaluation of Patients with Human Immunodeficiency Virus Infection / Michael W. Baseler, Randy A. Stevens, Ven Natarajan, Juan C. Gea-Banacloche, Julia A. Metcalf 758

86 Quantitation of Viremia and Determination of Drug Resistance in Patients with Human Immunodeficiency Virus Infection / T. Elbeik, T. W. Chun, H. Imamichi, T. Imamichi, V. Natarajan, D. Waters, R. L. Dewar, H. Highbarger 772

87 Principles and Procedures of Human Immunodeficiency Virus Serodiagnosis / M. B. Vasudevachari, Richard T. Davey, Jr., Julia A. Metcalf, Robin L. Dewar 790

Section L Immunodeficiency Diseases / Volume Editor: Robert G. Hamilton, Section Editor: Charlotte Cunningham-Rundles 805

89 Genetics of Inherited Immunodeficiency Diseases and Diagnostic Techniques / Christine Kinnon, Hubert B. Gaspar 810

90 Combined B- and T-Cell Deficiencies / Francisco A. Bonilla 819

91 Investigation of Signal Transduction Defects / Melissa E. Elder 826

92 Primary Antibody Deficiencies in Children and Adults / Alexander R. Lawton 830

93 Inherited and Acquired C1-Inhibitor Deficiency / Virginia H. Donaldson 837

94 Genetically Determined Deficiencies of the Complement System: C1, C4, C2, and C3 / Jerry A. Winkelstein, Rohan Ameratunga 842

95 Deficiencies of Mannose-Binding Lectin, the Alternative Pathway, and the Late Complement Components / Anders G. Sjoholm 847

96 Neutropenia and Neutrophil Defects / Steven M. Holland 855

Section M Allergic Diseases / Volume Editor: Robert G. Hamilton, Section Editor: Dennis Ownby 865

98 Quantitation and Standardization of Allergens / John W. Yunginger, Cheryl R. Adolphson, Mark C. Swanson 868

99 In Vivo Diagnostic Allergy Testing Methods / Philip S. Norman, R. Stokes Peebles 875

100 The Diagnostic Allergy Laboratory / William K. Dolen 883

101 Tests for Immunological Reactions to Drugs and Occupational Allergens / Marie-Noel Primeau, N. Franklin Adkinson, Jr. 891

102 Assay Methods for Measurement of Mediators and Markers of Allergic Inflammation / John T. Schroeder, Anne Kagey-Sobotka 899

103 Immunological Tests for Evaluation of Hypersensitivity Pneumonitis and Allergic Bronchopulmonary Aspergillosis / Viswanath P. Kurup, Jordan N. Fink 910

Section N Systemic Autoimmune Diseases / Volume Editor: Noel R. Rose, Section Editor: C. Kirk Osterland 919

105 Immunofluorescent Antinuclear Antibody Tests / Arthur R. Bradwell 922

106 Autoantibody Testing by Non-Fluorescein Isothiocyanate (FITC) Methods / Westley H. Reeves, Minoru Satoh, Daniel P. McCauliffe 933

107 Enzyme-Linked Immunosorbent Assays for Diagnostically Important Antinuclear Antibodies / Rufus W. Burlingame, Robert L. Rubin 951

108 Rheumatoid Factors / Mark H. Wener 961

109 Antiphospholipid Antibody Tests / Azzudin E. Gharavi, Michael D. Lockshin 973

110 Antineutrophil Cytoplasmic Antibodies (ANCAs) and ANCA Testing / Allan Wiik 981

Section O Organ-Localized Autoimmune Diseases / Volume Editor: Noel R. Rose, Section Editor: C. Lynne Burek 987

112 Endocrinopathies / C. L. Burek, P. E. Bigazzi, N. R. Rose, M. Zakarija, J. M. McKenzie, J. D. Marker, N. K. Maclaren 990

113 Autoantibody Profiles of Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome / Guy E. Griesmann, Thomas J. Kryzer, Vanda A. Lennon 1005

114 Autoimmune Autonomic Neuropathy and Neuromuscular Hyperexcitability Disorders / Steven Vernino, Thomas J. Kryzer, Vanda A. Lennon 1013

115 Autoantibodies to Glycolipids in Peripheral Neuropathy / Hugh J. Willison 1018

116 Detection of Antimitochondrial Autoantibodies in Primary Biliary Cirrhosis and Liver-Kidney Microsomal Antibodies in Autoimmune Hepatitis / Patrick S. C. Leung, Michael P. Manns, Ross L. Coppel, M. Eric Gershwin 1023

117 Skin Diseases / Hossein C. Nousari, Grant J. Anhalt 1032

118 Cardiovascular Diseases / J. B. Sundstrom, C. Lynne Burek, Noel R. Rose, A. A. Ansari 1043

119 Kidney and Lung Disease Mediated by Anti-Glomerular Basement Membrane Antibodies: Detection by Western Blot Analysis / A. Bernard Collins, Robert B. Colvin 1049

120 Autoimmunity of Testis, Ovary, and Spermatozoa / Kenneth S. K. Tung, Richard A. Bronson 1054

121 Immunologic Testing for Celiac Disease and Inflammatory Bowel Disease / James A. Goeken 1060

122 Autoimmune Thrombocytopenia / Thomas S. Kickler 1065

123 Autoimmune Hemolytic Anemia / Leigh C. Jefferies, Mary Elizabeth Smith 1070

Section P Cancer / Volume Editor: Noel R. Rose, Section Editor: Theresa L. Whiteside 1081

125 Human Tumor Antigens Recognized by T Cells / Charles F. Eisenbeis, Thomas F. Gajewski 1085

126 Cancer Vaccines / Jayakar V. Nayak, Louis D. Falo, Jr. 1091

127 Malignancies of the Lymphoid and Histiocytic Systems / Elaine S. Jaffe, Mark Raffeld 1098

128 Monitoring of Immunologic Therapies / Theresa L. Whiteside, Jacquelyn A. Hank 1108

129 The Future of Chip Technologies in Cancer Care and Research / Charles B. Foster, Stephen J. Chanock 1118

Section Q Transplantation Immunology and Immunogenetics / Volume Editor: Barbara Detrick, Section Editor: Mary S. Leffell 1125

130 Immunogenetics: Transplantation and Beyond / Mary S. Leffell 1127

131 HLA Typing by Molecular Methods / Carolyn Katovich Hurley, Ting Tang, Jennifer NG, Noriko Steiner, Robert J. Hartzman 1134

132 Evaluation of the Humoral Response in Transplantation / Andrea A. Zachary, Jeffrey T. Sholander, Nancy L. Delaney, Donna P. Lucas 1153

133 Evaluation of the Cellular Immune Response in Transplantation / Nancy L. Reinsmoen, Adriana Zeevi 1164

134 Histocompatibility Assessment in Bone Marrow Transplantation / Michael A. Pulsipher, Patrick G. Beatty 1176

135 Graft Engineering for Hematopoietic Stem Cell Transplantation / Paul V. O'Donnell, Kathy Loper, Stephen J. Noga 1187

136 Minor Histocompatibility Antigens / Martina Wilke, Els Goulmy 1201

Part III Administration 1209

Section R Laboratory Management / Volume Editor: Robert G. Hamilton, Section Editor: Ronald Harbeck 1211

138 Standardization of Immunoassay Methodologies / Carolyn S. Feldkamp, John L. Carey 1215

139 Quality Assurance / Peter J. Howanitz, Joan H. Howanitz 1227

140 Planning Statistical Quality Control Procedures / James O. Westgard 1239

141 Clinical Significance and Cost-Effectiveness of Clinical Immunology Testing / David F. Keren, Victor A. Hruszczyk 1251

142 Clinical Immunology Laboratory Accreditation, Licensure, and Credentials / Linda Cook, Ronald J. Harbeck 1258

143 Establishment and Verification of Reference Values / Earle W. Holmes 1271.

Notes:

Includes bibliographical references and indexes.

ISBN:

1555812155

OCLC:

48046233