Immunology : a comprehensive review / Darla J. Wise and Gordon R. Carter.

Format:

Book

Author/Creator:

Wise, Darla J.

Contributor:

Carter, G. R. (Gordon R.)

Language:

English

Subjects (All):

Immunology.

Immunity.

Medical Subjects:

Immunity.

Physical Description:

xii, 182 pages : illustrations ; 22 cm

Edition:

First edition.

Place of Publication:

Ames : Iowa State University Press, 2002.

Summary:

This concise student supplementary text covers all of the basics of immunology, including chapters on the origin and function of hemopoietic and lymphopoietic cells; non-specific immunity; antigens; complement; cell receptors and cytokines associated with the immune response; specific immune responses; responses to bacteria, fungi, protozoa, helminthes, and tumors. The organization follows a natural progression, beginning with basic concepts and proceeding to what immunity does to protect the body and what happens when things go wrong.-- Up-to-date chapters covering all aspects of immunology-- A thorough discussion of immunodiagnostic techniques and AIDS-- Excellent figures and tables illustrating principles and summarizing data-- End-of-chapter glossaries supplementing the cumulative glossary-- A comprehensive list of Milestones in Immunology

Contents:

1 Introducing Immunology 3

Milestones in Immunology 7

2 The Hemopoietic and Lymphopoietic Cells 13

The Hemopoietic System 13

The Lymphopoietic System 15

Lymphoid Organs 17

The Lymphatic System 17

3 Natural Immunity and Resistance 19

Natural or Native Immunity 19

Physical and Chemical Barriers 19

Inflammation 20

Fever 21

Phagocytosis 22

Extracellular Killing 23

Interferons 23

Natural Killer (NK) Cells 23

4 The Nature of Antigens 25

Haptens 26

B Lymphocytes 27

T Lymphocytes 29

Antigen Processing 29

5 The Complement System 31

Cascade 31

Cytolysis 32

Inflammation 32

Opsonization and Immune Adherence 33

The Classical Pathway 33

The Alternative Pathway 35

6 T Cell Receptors, Major Histocompatibility Complex, and Cytokines 37

T Cell Receptors 37

Major Histocompatibility Complex (MHC) 40

Cytokines 45

7 The Humoral Immune Response 49

Structure and Assembly of Antibodies/Immunoglobulins 49

Isotype/Class Switching 52

The Clonal Selection Theory of Antibody Production 54

Antibody Response and Antigen-Antibody Interactions 56

Primary and Secondary Humoral Immune Responses 57

8 The Cell-Mediated Immune Response 61

T Lymphocytes (T Cells) 61

Cell-Mediated Cytotoxicity 63

The Role of Macrophages 66

Immunopathology 67

9 The Immune System in Action 69

Immunity to Bacteria 69

Immunity to Viruses 72

Immunity to Fungi 76

Immunity to Protozoa and Helminths 78

Immunity to Tumors 81

Tumor Immunotherapy 85

10 Hypersensitivity Reactions Part I: Allergy and Anaphylaxis 89

Type 1 Immediate or Anaphylactic Hypersensitivity 89

Allergy and Anaphylaxis 89

11 Hypersensitivity Reactions Part II: Cytotoxic/Cytologic, Immune Complex, and Delayed-Type 101

Cytotoxic/Cytolytic Reactions 101

Immune Complex Disease 104

Type IV Delayed-Type Hypersensitivity 108

12 Autoimmunity 113

Development 113

Role of Heredity 114

Environment 115

Examples of Autoimmune Diseases 116

Diagnosis 118

Treatment 118

13 Immunodeficiencies 119

Primary Immunodeficiencies 119

Secondary Deficiencies 121

14 Transplantation and Graft Rejection 123

Rejection 123

15 Vaccination and Immunization 129

Natural and Artificial Immunization 129

Active Immunization 130

Vaccines 131

Current and New Vaccine Development 132

Passive Immunization 135

16 Immunodiagnostic Techniques 137

Antibody Detection and Measurement 137

Procedures 138

17 Human Immunodeficiency Virus (HIV) Infection and Acquired Immune Deficiency Syndrome (AIDS) 151

The Virus and Pathogenesis 153

Immunology 157

Vaccination 158

Diagnosis 159

Treatment 160

Immune Restoration 161.

Notes:

Includes bibliographical references and index.

ISBN:

0813815991

OCLC:

47756109