Circulating nucleic acids in plasma or serum II / editors, Y.M. Dennis Lo, Rossa W.K. Chiu, Philip J. Johnson.

Format:

Book

Contributor:

Lo, Y. M. Dennis.

Chiu, Rossa W. K.

Johnson, Philip J.

Series:

Annals of the New York Academy of Sciences ; v. 945.

Annals of the New York Academy of Sciences ; v. 945

Language:

English

Subjects (All):

Molecular diagnosis--Congresses.

Molecular diagnosis.

Nucleic acids--Analysis.

Nucleic acids.

Blood--Analysis.

Blood.

Tumor markers.

Nucleic Acids--blood.

Neoplasms--diagnosis.

Medical Subjects:

Nucleic Acids--blood.

Neoplasms--diagnosis.

Genre:

Conference papers and proceedings.

Physical Description:

xii, 295 pages : illustrations ; 25 cm.

Place of Publication:

New York : New York Academy of Sciences, 2001.

Contents:

Circulating Nucleic Acids in Plasma and Serum: An Overview / Y. M. Dennis Lo 1

Part I. Tumor DNA in Plasma and Serum

A Framework for the Molecular Classification of Circulating Tumor Markers / Philip J. Johnson 8

Microsatellite Alterations Detected in the Serum of Early Stage Breast Cancer Patients / Bret Taback, Armando E. Giuliano, Nora M. Hansen, Dave S. B. Hoon 22

A Possible Noninvasive Method for the Detection of Bladder Cancer in Patients: Microsatellite Analysis of Free DNA in Urine and Blood / Michael Utting, Wolfram Werner, Gabriele Muller, Jorg Schubert, Kerstin Junker 31

Epigenetic Tumor Markers in Plasma and Serum: Biology and Applications to Molecular Diagnosis and Disease Monitoring / Ivy H. N. Wong, Y. M. Dennis Lo, Philip J. Johnson 36

DNA-Based Detection of Prostate Cancer in Blood, Urine, and Ejaculates / Carsten Goessl, Markus Muller, Rudiger Heicappell, Hans Krause, Kurt Miller 51

Part II. Viral DNA as a Tumor Marker

Serum/Plasma Viral DNA: Mechanisms and Diagnostic Applications to Nasopharyngeal and Cervical Carcinoma / Apiwat Mutirangura 59

Quantitative Analysis of Epstein-Barr Virus DNA in Plasma and Serum: Applications to Tumor Detection and Monitoring / Y. M. Dennis Lo 68

Remarkable Application of Serum EBV EBER-1 in Monitoring Response of Nasopharyngeal Cancer Patients to Salvage Chemotherapy / Roger K. C. Ngan, W. H. Lau, Timothy T. C. Yip, William C. S. Cho, W. W. Cheng, C. K. P. Lim, K. K. Wan, E. Chu, I. Joab, V. Grunewald, Y. F. Poon, John H. C. Ho 73

Circulating Cell-Free Epstein-Barr Virus DNA Levels in Patients with EBV-Associated Lymphoid Malignancies / Kenny I. K. Lei, Lisa Y. S. Chan, Wing Y. Chan, Philip J. Johnson, Y. M. Dennis Lo 80

Gross Elevation of TT Virus Genome Load in the Peripheral Blood Mononuclear Cells of Cancer Patients / Sheng Zhong, Winnie Yeo, Mandy W. Tang, Xiao-Rong Lin, Frankie Mo, Wing M. Ho, Pun Hui, Philip J. Johnson 84

Part III. Other Approaches for Cancer Detection

Circulating Nucleosomes in Serum / Stefan Holdenrieder, Petra Stieber, Heinz Bodenmuller, Martin Busch, Joachim von Pawel, Andreas Schalhorn, Dorothea Nagel, Dietrich Seidel 93

Proteomic Approaches within the NCI Early Detection Research Network for the Discovery and Identification of Cancer biomarkers / Mukesh Verma, George L. Wright Jr., Samir M. Hanash, Rashmi Gopal-Srivastava, Sudhir Srivastava 103

Detection of Circulating CEA Molecules in Human Sera and Leukopheresis of Peripheral Blood Stem Cells with E. coli Expressed Bispecific CEAScFv-Streptavidin Fusion Protein-Based Immuno-PCR Technique / Jun Ren, Le Ge, Yongqi Li, Jun Bai, Wen Chao Liu, Xiao Ming Si 116

Part IV. Fetal DNA and Cells in Maternal Blood

Fetomaternal Cellular and Plasma DNA Trafficking: The Yin and the Yang / Diana W. Bianchi, Y. M. Dennis Lo 119

Quantitative Analysis of Fetal DNA in Maternal Plasma in Pathological Conditions Associated with Placental Abnormalities / Maddalena Smid, Antonia Vassallo, Fiorenza Lagona, Luca Valsecchi, Lucia Maniscalco, Luana Danti, Andrea Lojacono, Augusto Ferrari, Maurizio Ferrari, Laura Cremonesi 132

Circulatory Fetal and Maternal DNA in Pregnancies at Risk and Those Affected by Preeclampsia / Xiao Yan Zhong, Wolfgang Holzgreve, Sinuhe Hahn 138

Both Maternal and Fetal Cell-Free DNA in Plasma Fluctuate / Sinuhe Hahn, Xiao Yan Zhong, Martin R. Burk, Carolyn Troeger, Anjeung Kang, Wolfgang Holzgreve 141

Use of Annexin V Antibody to Identify Apoptotic Cells during Pregnancy / Aggeliki Kolialexi, George T. H. Tsangaris, Ariadni Mavrou, Aristides Antsaklis, Fotini Tzortzatou, Vassiliki Touliatou, Catherine Metaxotou 145

Detection of Fetal NRBCs in Maternal Blood of Pregnant Carriers of [beta]-Thalassemia Using Anti-[gamma] and Anti-[epsiv] Monoclonal Antibodies / Ariadni Mavrou, Aggeliki Kolialexi, Aristides Antsaklis, Xenofon Krikos, Asteris Koratzis, Catherine Metaxotou 151

Fetal DNA Diagnosis from Maternal Blood: PEP-TaqMan PCR Analysis of a Single Nucleated Erythrocyte (NRBC) / K. Ikawa, K. Yamafuji, T. Ukita, S. Kuwabara, T. Igarashi, H. Takabayashi 153

Technical Optimization of RhD Zygosity Determination by Real-Time Quantitative Polymerase Chain Reaction: Implication for Fetal RhD Status Determination by Maternal Plasma / Rossa W. K. Chiu, Michael F. Murphy, Carrie Fidler, James S. Wainscoat, Y. M. Dennis Lo 156

Detection of Maternal DNA in Umbilical Cord Plasma by Fluorescent PCR Amplification of Short Tandem Repeat Sequences / Margit Bauer, Irmgard Orescovic, Wolfgang M. Schoell, Diana W. Bianchi, Barbara Pertl 161

From the Simple Detection of Microchimerism in Patients with Autoimmune Diseases to Its Implication in Pathogenesis / N. C. Lambert, A. M. Stevens, T. S. Tylee, T. D. Erickson, D. E. Furst, J. L. Nelson 164

Part V. Circulating RNA in Plasma and Serum: Towards Noninvasive Gene Expression Profiling

Circulating RNA as a Tumor Marker: Detection of 5T4 mRNA in Breast and Lung Cancer Patient Serum / Michael S. Kopreski, Floyd A. Benko, Christopher D. Gocke 172

Detection of Amplifiable Messenger RNA in the Serum of Patients with Lung Cancer / Michael Fleischhacker, Thomas Beinert, Michael Ermitsch, Dzemile Seferi, Kurt Possinger, Claus Engelmann, Burkhard Jandrig 179

Detection of Tumor-Associated Circulating mRNA in Patients with Disseminated Malignant Melanoma / G. Rappl, D. O. Hasselmann, M. RoBler, S. Ugurel, W. Tilgen, U. Reinhold 189

Detection of Mammaglobin mRNA in the Plasma of Breast Cancer Patients / Shira Gal, Carrie Fidler, Y. M. Dennis Lo, Kenny Chin, John Moore, Adrian L. Harris, James S. Wainscoat 192

Hepatitis B Virus Nucleic Acids Circulating in the Blood: Distinct Patterns in HBs Carriers with Hepatocellular Carcinoma / Raoul Breitkreutz, Wei Zhang, Mieun Lee, Armin Hoffmann, Mehmet Tokus, Qin Su, Claus H. Schroder 195

Circulating Fetal RNA in Maternal Plasma / Leo L. M. Poon, Tse N. Leung, Tze K. Lau, Y. M. Dennis Lo 207

Part VI. New Applications of Circulating DNA

Derivation of a Prediction Rule for Posttraumatic Organ Failure Using Plasma DNA and Other Variables / Timothy H. Rainer, Y. M. Dennis Lo, Lisa Y. S. Chan, Nicole Y. L. Lam, Lydia C. W. Lit, Robert A. Cocks 211

Low-Molecular-Weight DNA in Blood Plasma as an Index of the Influence of Ionizing Radiation / Irina N. Vasilyeva 221

Postradiation DNA Polymorphism / Sophia S. Sherlina, Viktor G. Vladimirov 229

Detection of Plasmodium falciparum DNA in Plasma / Shira Gal, Carrie Fidler, Sue Turner, Y. M. Dennis Lo, David J. Roberts, James S. Wainscoat 234

Part VII. Urinary DNA

Circulating Nucleic Acids and Apoptosis / Anatoly V. Lichtenstein, Hovsep S. Melkonyan, L. David Tomei, Samuil R. Umansky 239

Cell-Free DNA in Urine: A Marker for Kidney Graft Rejection, but Not for Prenatal Diagnosis? / Xiao Yan Zhong, Deirdre Hahn, Carolyn Troeger, Andre Klemm, Gunter Stein, Peter Thomson, Wolfgang Holzgreve, Sinuhe Hahn 250

Part VIII. Biological Issues in Circulating Nucleic Acids

Alu Repeat Sequences Are Present in Increased Proportions Compared to a Unique Gene in Plasma/Serum DNA: Evidence for a Preferential Release from Viable Cells? / Maurice Stroun, Jacqueline Lyautey, Christine Lederrey, Hugh E. Mulcahy, Philippe Anker 258

Functionality of Circulating DNA: The Hypothesis of Genometastasis / Damian Garcia-Olmo, Dolores C. Garcia-Olmo 265

Foreign DNA Integration

Perturbations of the Genome

Oncogenesis / Walter Doerfler, Urte Hohlweg, Knut Muller, Ralph Remus, Hilde Heller, Jennifer Hertz 276

Possible Origin of Extrachromosomal DNA from Human Lymphocytes Following In Vitro Treatment by Phytohemagglutinin / John S. Chen, Maria G. Menesini Chen 289.

Notes:

Includes bibliographical references and index.

ISBN:

1573313785

1573313793

OCLC:

47254295