The Chemotherapy source book / edited by Michael C. Perry.

Format:

Book

Contributor:

Perry, Michael C. (Michael Clinton), 1945-

Language:

English

Subjects (All):

Cancer--Chemotherapy.

Cancer.

Antineoplastic agents.

Neoplasms--drug therapy.

Antineoplastic Agents--therapeutic use.

Medical Subjects:

Neoplasms--drug therapy.

Antineoplastic Agents--therapeutic use.

Physical Description:

xiii, 1003 pages : illustrations ; 29 cm

Edition:

Third edition.

Place of Publication:

Philadelphia : Lippincott Williams & Wilkins, [2001]

Summary:

The updated Third Edition of The Chemotherapy Source Book is the most current and comprehensive reference on cancer chemotherapy. It brings together pharmacologic and patient management information in one source that practitioners can consult for any question encountered in the delivery of chemotherapy. This edition features increased information on the expanding use of high-dose therapy for various cancers, including breast cancer, leukemias, multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphoma, lung cancer, and ovarian cancer. Coverage also includes new material on monoclonal antibodies, monoclonal antibody therapy, and breast, colon, and lung cancers, and information on five new drugs approved since the Second Edition. A Brandon-Hill recommended title.

Contents:

1. Scientific Basis of Cancer Chemotherapy / James K. Schwarz, John W. Yarbro 1

2. Antineoplastic Drug Development / Robert I. Haddad, David A. Van Echo 6

3. Principles of Pharmacology / Antonius A. Miller, Mark J. Ratain, Richard L. Schilsky 14

4. Norton-Simon Hypothesis / Teresa A. Gilewski, Larry Norton 23

5. Drug Resistance / James H. Goldie 37

6. Adjuvant Chemotherapy / Andrew M. Evens, Jacob D. Bitran 48

7. Combination Chemotherapy / Howard A. Burris III 69

8. Combined Modality Therapy / Mark P. Bryer 73

9. Design and Interpretation of Clinical Trials / Richard Simon, Michael A. Friedman 81

10. Clinical Trials / Barbara K. Barrett 89

11. Hematopoietic Growth Factors / Jeffrey Crawford, Susan Blackwell 94

12. Biologic Response Modifiers: Principles of Biotherapy / Ashok Beedassy, Howard Ozer 105

13. Circadian Timing of Cancer Chemotherapy / Patricia A. Wood, William J. M. Hrushesky 114

Part B Routes of Administration

14. Intraventricular and Intrathecal Therapy / Arthur Forman, Victor A. Levin 132

15. Intraperitoneal Chemotherapy / Maurie Markman 141

16. Continuous Intravenous Infusion Chemotherapy / Robert W. Carlson 144

17. Intraarterial Therapy / William D. Ensminger 163

18. Perfusion Therapy / Michael S. Sabel, William G. Kraybill 174

19. Hematopoietic Stem Cell Transplantation / Steven Z. Pavletic, James O. Armitage 185

Section II Chemotherapeutic Drugs

20. Covalent DNA-Binding Drugs / Louise B. Grochow 192

21. Antimetabolites / John C. Gutheil, Deborah M. Finucane 208

22. Antitumor Antibiotics and Related Compounds / Charles E. Riggs, Jr. 227

23. Microtubule-Targeting Drugs / Eric Keith Rowinsky, Anthony W. Tolcher 252

24. DNA Topoisomerase II Inhibitors / Anthony W. Tolcher, Eric Keith Rowinsky 278

25. Topoisomerase I-Targeting Drugs / Eric Keith Rowinsky, Anthony W. Tolcher 289

26. Differentiation Agents / Raymond P. Warrell, Jr. 304

27. Hormones / Robert S. DiPaola, Michael Reiss, Joseph Aisner 312

28. L-Asparaginase / Alan P. Lyss 323

29. Investigational Drugs / Daniel R. Budman, Varun Gupta 325

30. Antibodies / Haleem J. Rasool 394

Section III Management of Drug Toxicity

31. Hematologic Complications of Cancer Chemotherapy / Rasa L. Buntinas, Raymond J. Hohl 399

32. Oral Toxicity / Douglas E. Peterson, Mark M. Schubert 406

33. Dermatologic Toxicity / Antoinette F. Hood, Matthew C. Reeck 424

34. Extravasation / Gerald H. Clamon 432

35. Hypersensitivity Reactions / Raymond B. Weiss 436

36. Ocular Side Effects of Chemotherapy / Linda J. Burns 452

37. Cardiotoxicity of Chemotherapeutic Drugs / Michael S. Ewer, Robert S. Benjamin 458

38. Chemotherapy-Associated Lung Injury / James M. Hinson, Jr., Andrew W. McKibben 468

39. Gastrointestinal Complications of Chemotherapy / Dayna S. Early 477

40. Hepatotoxicity of Chemotherapeutic Agents / Paul D. King, Michael C. Perry 483

41. Renal and Electrolyte Abnormalities Due to Chemotherapy / William P. Patterson, Garry P. Reams 494

42. Neurotoxicity of Chemotherapy Agents / Michael A. Meyer 504

43. Vascular Toxicity / Donald C. Doll 514

44. Second Malignancies after Chemotherapy / John D. Boice, Jr. 526

45. Chemotherapy in Pregnancy / Irfan Maghfoor, Donald C. Doll 537

46. Gonadal Complications and Teratogenicity of Cancer Therapy / Catherine E. Klein 546

Section IV Drug Administration

47. Central Venous Access for Chemotherapy / Steven B. Standiford 559

48. Risks of Handling Cytotoxic Drugs / Bruce R. Harrison 566

49. Patient Education / Mary H. Johnson, Verna A. Rhodes 583

Section V Current Therapy of Specific Solid Tumors

50. Chemotherapy of Melanoma / Clay M. Anderson 596

51. Chemotherapy of Primary Brain Tumors / Susanne M. Arnold, Roy A. Patchell 602

52. Chemotherapy of Head and Neck Cancer / Everett E. Vokes, Gary S. Gordon 610

53. Chemotherapy of Lung Cancer / Jimmy J. Hwang, Chandra P. Belani 626

54. Chemotherapy of Breast Cancer / Carl G. Kardinal, John T. Cole 647

55. Chemotherapy of Gastrointestinal Cancer / James E. Wooldridge 689

56. Chemotherapy of Endocrine Tumors / John L. Visconti, Alan B. Silverberg, Kent R. Wehmeier 698

57. Chemotherapy of Genitourinary Cancers / Christopher W. Ryan, Nicholas J. Vogelzang 710

58. Chemotherapy of Gynecologic Cancer / Jeffrey D. Bloss, James Tate Thigpen 732

59. Chemotherapy of Sarcomas of Bone and Soft Tissue / Haralambos Raftopoulos, Karen Antman 760

60. Chemotherapy of Carcinoma of Unknown Primary Site / John D. Hainsworth, F. Anthony Greco 778

61. Chemotherapy of Pediatric Solid Tumors / Donald K. Strickland 788

Section VI Chemotherapy of Hematologic Malignancies

62. Chemotherapy of Hodgkin's Disease / Bruce A. Peterson 795

63. Chemotherapy of Non-Hodgkin's Lymphoma / Philip J. Bierman, James O. Armitage 810

64. Chemotherapy of Acute Leukemia in Adults / Charles F. Eisenbeis, Richard A. Larson 824

65. Chemotherapy and Immunotherapy of Chronic Lymphocytic Leukemia and Hairy Cell Leukemia / John C. Byrd, Kanti R. Rai 839

66. Chemotherapy of the Myelodysplastic Syndromes / Bruce D. Cheson 849

67. Management of Chronic Myeloproliferative Disorders and Chronic Myelocytic Leukemia / Ayalew Tefferi 857

68. Chemotherapy of Multiple Myeloma and Related Plasma Cell Dyscrasias / Haleem J. Rasool, Mehdi Farhangi 865

Chemotherapy Programs / James E. Wooldridge 876

Common Toxicity Criteria / National Cancer Institute 905.

Notes:

Includes bibliographical references and index.

ISBN:

0781723639

OCLC:

46315364