Mechanisms of lymphocyte activation and immune regulation VIII : autoimmunity 2000 and beyond / edited by Sudhir Gupta.

Format:

Book

Contributor:

Gupta, Sudhir.

Series:

Advances in experimental medicine and biology ; v. 490.

Advances in experimental medicine and biology ; v. 490

Language:

English

Subjects (All):

Pathogenesis.

Autoimmunity.

Autoimmune diseases--Pathogenesis.

Autoimmune diseases.

Autoimmune Diseases--therapy.

Lymphocyte Activation.

Lymphocytes--immunology.

Medical Subjects:

Autoimmunity.

Autoimmune Diseases--therapy.

Lymphocyte Activation.

Lymphocytes--immunology.

Physical Description:

viii, 136 pages : illustrations ; 26 cm.

Other Title:

Autoimmunity 2000 and beyond

Place of Publication:

New York : Kluwer Academic/Plenum, [2001]

Summary:

Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.

Notes:

Includes bibliographical references and index.

ISBN:

0306465701

OCLC:

45799987