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Principles and practice of psychopharmacotherapy / Philip G. Janicak ... [and others].

Holman Biotech Commons RC483 .P74 2001
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Format:
Book
Contributor:
Janicak, Philip G.
Language:
English
Subjects (All):
Mental illness--Chemotherapy.
Mental illness.
Psychopharmacology.
Mental Disorders--drug therapy.
Psychotropic Drugs--metabolism.
Psychotropic Drugs--therapeutic use.
Medical Subjects:
Mental Disorders--drug therapy.
Psychotropic Drugs--metabolism.
Psychotropic Drugs--therapeutic use.
Physical Description:
xv, 700 pages : illustrations ; 26 cm
Edition:
Third edition.
Other Title:
Psychopharmacotherapy
Place of Publication:
Philadelphia : Lippincott Williams & Wilkins, [2001]
Summary:
Completely updated in its Third Edition, this text provides an evidence-based approach to the clinical use of today's psychotropic drugs. The book comprehensively summarizes the scientific and clinical research literature and offers treatment strategies that flow directly from scientific data. The first chapter sets forth key principles of psychopharmacotherapy, foremost of which is the thorough assessment of the patient's history that helps establish the appropriate role of drug therapy. Subsequent chapters discuss the major categories of psychiatric drugs, present strategies for their therapeutic use, and discuss meta-analyses of clinical and scientific studies. Concluding chapters address anxiety disorders and special populations. Each chapter has user-friendly features such as highlighted/italicized text, tables, bulleted lists, and diagrams.
Contents:
Principles of Psychopharmacotherapy 1
Role of Neuroscience 6
Diagnostic Assessment 8
Role of the Laboratory 11
2. Assessment of Drug Efficacy and Relevant Clinical Issues 27
Evaluation of Drug Study Designs 27
Statistical Summarization of Drug Studies 32
Patient Issues 38
Drug Management 44
Role of the Food and Drug Administration 45
Cost of Treatment 48
3. Pharmacokinetics 51
Four Primary Pharmacokinetic Phases 51
Alterations in Pharmacokinetics 61
Therapeutic Drug Monitoring 64
Clinical Application of Pharmacokinetic Principles 65
4. Indications for Antipsychotics 73
Schizophrenia 73
Other Psychotic Disorders 77
Nonpsychotic Disorders 80
5. Treatment with Antipsychotics 83
Mechanism of Action 84
Effects on Cognition and Behavior 90
Management of Acute Psychosis 93
Maintenance/Prophylaxis 116
Long-Acting Antipsychotics 130
Pharmacokinetics/Plasma Levels 133
Alternative Treatment Strategies 141
Role of Psychosocial Therapies 147
Adverse Effects 152
6. Indications for Antidepressants 193
Depressive Disorders 193
Suicide 207
Other Costs of Major Depression 212
7. Treatment with Antidepressants 215
Mechanism of Action 215
Management of an Acute Depressive Episode 225
Maintenance/Prophylaxis 255
Pharmacokinetics 262
Therapeutic Drug Monitoring 268
Alternative Treatment Strategies 274
Role of Psychosocial Therapies 278
Adverse Effects 281
Drug-Drug Interactions 298
8. Treatment with Electroconvulsive Therapy and Other Somatic Therapies 327
Electroconvulsive Therapy 327
Other Somatic Therapies 354
9. Indications for Mood Stabilizers 369
Bipolar Disorder 369
10. Treatment with Mood Stabilizers 383
Mechanism of Action 384
Management of an Acute Manic Episode 389
Maintenance/Prophylaxis 402
Adverse Effects of Lithium, Valproate, and Other Anticonvulsants 435
Adverse Effects of Other Drugs 451
11. Indications for Antianxiety and Sedative-Hypnotic Agents 463
Generalized Anxiety Disorder 463
Phobic Disorders 464
Psychological Factors Affecting a Medical Condition 465
Sleep Disorders 465
12. Treatment with Antianxiety and Sedative-Hypnotic Agents 471
BZD: Mechanism of Action 473
Treatment of Generalized Anxiety Disorder 474
Treatment of Phobic Disorders 481
Treatment of Sleep Disorders 482
Pharmacokinetics 495
Adverse Effects of Anxiolytics 498
Adverse Effects of Sedative-Hypnotics 510
13. Assessment and Treatment of Other Disorders 523
Panic Disorder 523
Obsessive-Compulsive Disorder 535
Trichotillomania 544
Posttraumatic Stress Disorder 546
Dissociative Disorders 548
14. Assessment and Treatment of Special Populations 559
The Pregnant Patient 559
The Child and Adolescent Patient 563
The Personality-Disordered Patient 584
The Elderly Patient 590
The Dying Patient 601
The Alcoholic Patient 606
The Human Immunodeficiency Virus-Infected Patient 615
The Eating-Disordered Patient 620.
Notes:
Includes bibliographical references and index.
ISBN:
0781727944
OCLC:
45800161

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