Adrenal disorders / edited by Andrew N. Margioris and George P. Chrousos.

Format:

Book

Contributor:

Margioris, Andrew N.

Chrousos, George P.

Series:

Contemporary endocrinology (Totowa, N.J.)

Contemporary endocrinology

Language:

English

Subjects (All):

Adrenal glands--Pathophysiology.

Adrenal glands.

Adrenal glands--Physiology.

Adrenal Cortex Diseases--physiopathology.

Adrenal Cortex--physiology.

Adrenal Gland Diseases--physiopathology.

Adrenal Medulla--physiology.

Physiology.

Medical Subjects:

Adrenal Cortex Diseases--physiopathology.

Adrenal Cortex--physiology.

Adrenal Gland Diseases--physiopathology.

Adrenal Medulla--physiology.

Physical Description:

xi, 424 pages : illustrations ; 26 cm.

Place of Publication:

Totowa, N.J. : Humana Press, [2001]

Summary:

In Adrenal Disorders, a panel of distinguished physicians and researchers select the most relevant new findings and integrate them into the existing body of clinical knowledge on adrenal pathologies. The book includes important reviews of disturbances in cortisol homeostasis, and new concepts regarding adrenal tumors and hereditary adrenal diseases. Also discussed are mineralocorticoids and the syndromes of mineralocortoid excess and aldosterone synthase deficiency. Authoritative and insightful, Adrenal Disorders provides physicians and scientists with a comprehensive, state-of-the-art practical guide to the devastating diseases of the adrenals that are so often difficult to diagnose and treat.

Contents:

Part I. The Adrenal Gland: Physiology

1 Ontogeny of the Hypothalamo-Pituitary-Adrenal Axis / Michel Grino, Nadia Dakine, Odile Paulmyer-Lacroix, Charles Oliver 1

2 Adrenal Organogenesis and Steroidogenesis: Role of Nuclear Receptors Steroidogenic Factor-1, DAX-1, and Estrogen Receptor / Meera S. Ramayya 11

3 Reappraisal of Adrenal Zonation Theories Based on the Differential Regulation of Apoptosis / G. W. Wolkersdorfer, S. R. Bornstein 45

4 Pharmacology of Glucocorticoids: An Overview / Achille Gravanis, Andrew N. Margioris 59

5 Glucocorticoid Catabolism and the 11[beta]-Hydroxysteroid Dehydrogenase System / Jonathan R. Seckl 71

6 Androgens of Adrenal Origin / George Mastorakos, Anthony G. Doufas 81

7 Structure, Function, and Regulated Expression of the Steroidogenic Acute Regulatory (StAR) Protein: Molecular Insights Into the Acute Steroidogenic Response of the Adrenals and Gonads to Trophic Stimulation / Caleb B. Kallen, Futoshi Arakane, Teruo Sugawara, Marianthi Kiriakidou, Staci E. Pollack, Hidemichi Watari, Lane K. Christenson, Michiko Watari, Jerome F. Strauss III 107

8 Regulation of Adrenocortical Function by the Sympathoadrenal System: Physiology and Pathology / Monika Ehrhart-Bornstein, Stefan R. Bornstein 119

9 Interleukin (IL)-1 Family of Cytokines and Corticotropin-Releasing Hormone (CRH) in the Adrenal Gland / Andrew N. Margioris, Erene Dermitzaki, Maria Venihaki, Achille Gravanis 131

Part II. The Adrenal Gland: Pathophysiology

10 Overview of Hyper- and Hypocortisolism / W. W. de Herder, S. W. J. Lamberts 143

11 ACTH Resistance / Constantine Tsigos 155

12 Syndromes of Ectopic ACTH Secretion: Recent Pathophysiological Aspects / Yves de Keyzer, Marie Laure Raffin-Sanson, Agnes Picon, Xavier Bertagna 165

13 Clinical Presentation and Diagnosis of Cushing's Syndrome / Andrew N. Margioris, George P. Chrousos 179

14 The Desmopressin Test: A New Tool in the Functional Evaluation of the Pituitary-Adrenal Axis in Patients with Cushing's Syndrome? / S. Tsagarakis, N. Thalassinos 193

15 Pseudo-Cushing Syndrome / Theodore Friedman 203

16 Adrenocortical Tumors and Oncogenes / Martin Reincke 219

17 Management of Adrenal Cancer / David E. Schteingart, Dominic Homan 231

18 Adrenal Incidentalomas / Bruno Allolio 249

19 Congenital Adrenal Hyperplasia: 21-Hydroxylase Deficiency / Maria I. New 263

20 Steroid 11[beta]-Hydroxylase Deficiency / Perrin C. White 273

21 Micronodular Adrenal Disease and the Syndrome of Myxomas, Spotty Skin Pigmentation, and Endocrine Overactivity / Constantine A. Stratakis 283

22 Congenital Lipoid Adrenal Hyperplasia / Walter L. Miller 291

23 Congenital Adrenal Hypoplasia / Michael Peter, Wolfgang G. Sippell 303

24 The HPA Axis and HIV Infection / Daniel S. Donovan, Jr., Robert G. Dluhy 317

25 Hypothalamic-Pituitary-Adrenal Axis and Obesity / Per Bjorntorp, Roland Rosmond 329

26 Aldosterone Synthase Deficiency / Michael Peter, Wolfgang G. Sippell 339

27 Mineralocorticoid Excess Syndromes / Richard D. Gordon 355

28 Pheochromocytoma: Progress in Diagnosis, Therapy, and Genetics / Karel Pacak, George P. Chrousos, Christian A. Koch, Jacques W. M. Lenders, Graeme Eisenhofer 379.

Notes:

Includes bibliographical references and index.

ISBN:

0896034119

OCLC:

46548632