Angiotensin II receptor antagonists / edited by Murray Epstein, Hans R. Brunner.

Format:

Book

Contributor:

Epstein, Murray, 1937-

Brunner, Hans R., 1937-

Language:

English

Subjects (All):

Angiotensin II--physiology.

Angiotensin II--antagonists & inhibitors.

Receptors, Angiotensin--physiology.

Medical Subjects:

Angiotensin II--physiology.

Angiotensin II--antagonists & inhibitors.

Receptors, Angiotensin--physiology.

Physical Description:

xiv, 384 pages : illustrations ; 24 cm

Other Title:

Angiotensin 2 receptor antagonists

Angiotensin two receptor antagonists

Place of Publication:

Philadelphia : Hanley & Belfus, [2001]

Contents:

I. Angiotensins and Their Receptors

1. Species Variations in the Renin-Angiotensin System: Therapeutic Implications / Norman K. Hollenberg, M.D., Ph.D. 1

2. Bioactive Angiotensin Peptides Other Than Angiotensin II / Duncan J. Campbell, M.D., Ph.D. 9

3. Angiotensin Receptors: An Overview / Ying-Hong Feng, M.D., Ph.D., Janice G. Douglas, M.D. 29

4. Signaling and Cellular Effects of Angiotensin II / Raymond C. Harris, M.D. 49

5. Circulating versus Tissue Angiotensin II / Jurg Nussberger, M.D. 69

II. Blockade of the Renin-Angiotensin System

6. Early Experience with Angiotensin II Receptor Antagonists and Angiotensin-Converting Enzyme Inhibitors / Hans R. Brunner, M.D., Haralambos Gavras, M.D. 79

7. Development of Nonpeptidic Angiotensin II Receptor Antagonists / Pieter B.M.W.M. Timmermans, Ph.D. 89

8. Distinction Between Surmountable and Insurmountable Angiotensin II AT[subscript 1] Receptor Antagonists / Georges Vauquelin, Ph.D., Frederik Fierens, M.Sc., Patrick Vanderheyden, Ph.D. 105

III. Experimental Studies of the Effects of Angiotensin II and At[subscript 1] Receptor Blockade

9. Does the Renin-Angiotensin System Exert an Important Stimulatory Influence on the Sympathetic Nervous System? / Murray Esler, M.D., Ph.D., Hans Peter Brunner-La Rocca, M.D. 119

10. Angiotensin and the Central Nervous System / Andrew M. Allen, Ph.D., Michael J. McKinley, Ph.D., D.Sc., Joohyung H. Lee, B.Sc. (Hons.), Frederick A. O. Mendelsohn, M.D., Ph.D., FRACP 129

11. Interaction of AT[subscript 1] Receptor Antagonists and Other Vasoactive Factors / Ahmed G. Adam, M.D., Ph.D., Areef Ishani, M.D., Rahul Koushik, M.D., Leopoldo Raij, M.D. 149

12. Mechanism for Chronic Antihypertensive Effect of Angiotensin II Blockade / Michael W. Brands, Ph.D., John E. Hall, Ph.D. 171

13. Renal Actions of Angiotensin II and AT[subscript 1] Receptor Blockers / L. Gabriel Navar, Ph.D., Lisa M. Harrison-Bernard, Ph.D., John D. Imig, Ph.D., Kenneth D. Mitchell, Ph.D. 189

14. Cardiac Effects of Angiotensin II and AT[subscript 1] Receptor Blockade / Irene Gavras, M.D., Haralambos Gavras, M.D. 215

15. Wall Stress, Angiotensin II, and Left Ventricular Hypertrophy / Trefor O. Morgan, M.B.B.S., B.Sc., M.D., Cory D. Griffiths, Ph.D., Lea M. D. Delbridge, Ph.D. 223

16. Vascular Effects of Angiotensin II and AT[subscript 1] Receptor Blockade / Sharon L. Grant, Ph.D., Kathy K. Griendling, Ph.D. 235

IV. Clinical Experience with AT[subscript 1] Receptor Antagonists

17. Angiotensin II Receptor Antagonists: Current Status / Murray Epstein, M.D., FACP 257

18. AT[subscript 1] Receptor Antagonists as Antihypertensive Agents / Maurice E. Fabiani, M.D., Colin I. Johnston, M.D. 263

19. Role of AT[subscript 1] Angiotensin Receptors in Vascular Remodeling in Hypertension / Ernesto L. Schiffrin, M.D., Ph.D., FRCPC, FACP, Daniel Hayoz, M.D. 279

20. AT[subscript 1] Receptor Antagonists and the Kidney / R.T. Gansevoort, M.D., Ph.D., A. Mimran, M.D., Ph.D., D. de Zeeuw, M.D., Ph.D., Bernard Jover, Ph.D. 295

21. Evolving Role of Angiotensin II Receptor Antagonists in Diabetes Mellitus / Mark Cooper, M.D., Ph.D., FRACP, Murray Epstein, M.D., FACP 317

22. AT[subscript 1] Receptor Antagonists in Combination with Other Antihypertensive Agents / Bernard Waeber, M.D., Hans R. Brunner, M.D. 329

23. Angiotensin II Receptor Antagonists: Safety and Tolerability Profile / Lucia Mazzolai, M.D., Michel Burnier, M.D. 339

V. Ongoing Trials with AT[subscript 1] Receptor Antagonists

24. Morbidity and Mortality Trials with Angiotensin Receptor Antagonists in Hypertensive Patients / Alberto Zanchetti, M.D. 351

25. Evolving Perspectives and Future Challenges / Hans R. Brunner, M.D., Murray Epstein, M.D., FACP 361.

Notes:

Includes bibliographical references and index.

ISBN:

1560534532

OCLC:

44128565