Cerebral amyloid angiopathy in Alzheimer's disease and related disorders / edited by Marcel M. Verbeek, Robert M.W. de Waal, Harry V. Vinters.

Format:

Book

Contributor:

Verbeek, Marcel M.

De Waal, Robert M. W.

Vinters, Harry V.

Language:

English

Subjects (All):

Cerebral Amyloid Angiopathy.

Alzheimer Disease.

Medical Subjects:

Cerebral Amyloid Angiopathy.

Alzheimer Disease.

Physical Description:

xix, 357 pages : illustrations ; 25 cm

Place of Publication:

Dordrecht ; Boston : Kluwer, 2000.

Contents:

Section I Clinical Aspects of CAA and CAA-Related Hemorrhage

Chapter 1 Clinical aspects and diagnostic criteria of sporadic CAA-related hemorrhage / Steven M. Greenberg 3

Chapter 2 Diagnosis of CAA during life. Neuroimaging of CAA / Ulrich Bickel 21

Chapter 3 Vascular risk factors for Alzheimer's disease. An epidemiologic perspective / Monique M.B. Breteler 43

Chapter 4 Cerebral microvascular and macrovascular disease in the aging brain; similarities and differences / Harry V. Vinters 59

Section II Genetics of CAA

Chapter 5 ApoE genotype in relation to sporadic and Alzheimer-related CAA / Mark O. McCarron, James A.R. Nicoll 81

Chapter 6 Clinical and genetic aspects of hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D) / Marjolijn Bornebroek, Joost Haan, Egbert Bakker, Raymund A.C. Roos 103

Chapter 7 Genetics and neuropathology of hereditary cystatin C amyloid angiopathy (HCCAA) / Isleifur Olafsson, Leifur Thorsteinsson 121

Section III Cellular and Molecular Pathology of CAA

Chapter 8 Neuropathologic features and grading of Alzheimer-related and sporadic CAA / Harry V. Vinters, Jean-Paul G. Vonsattel 137

Chapter 9 Chemical analysis of amyloid [beta] protein in CAA / Alex E. Roher, Yu-Min Kuo, Alexander A. Roher, Mark R. Emmerling, Warren J. Goux 157

Chapter 10 Immunohistochemical analysis of amyloid [beta] protein isoforms in CAA / Haruyasu Yamaguchi, Marion L.C. Maat-Schieman 179

Chapter 11 Blood Brain Barrier dysfunction and cerebrovascular degeneration in Alzheimer's disease / Raj N. Kalaria 189

Chapter 12 A[beta]-associated proteins in cerebral amyloid angiopathy / Robert M.W. de Waal, Marcel M. Verbeek 207

Chapter 13 Neuropathology of hereditary cerebral hemorrhage with amyloidosis-Dutch type / Marion L.C. Maat-Schieman, Sjoerd G. Van Duinen, Remco Natte, Raymund A.C. Roos 223

Chapter 14 Neuropathology and genetics of prion protein and British cerebral amyloid angiopathies / Bernardino Ghetti, Pedro Piccardo, Blas Frangione, Ruben Vidal, Jorge Ghiso 237

Section IV In Vitro and Animal Models of CAA

Chapter 15 Amyloid [beta] protein internalization and production by canine smooth muscle cells / Reinhard Prior, Britta Urmoneit 251

Chapter 16 Degeneration of human cerebrovascular smooth muscle cells and pericytes caused by amyloid [beta] protein / Marcel M. Verbeek, William E. Van Nostrand, Robert M.W. de Waal 265

Chapter 17 Vasoactivity of amyloid [beta] peptides / Daniel Paris, Terrence Town, Michael Mullan 281

Chapter 18 CAA in transgenic mouse models of Alzheimer's disease. What can we learn from APP transgenic mouse models? / Greg M. Cole, Fusheng Yang 295

Chapter 19 Cerebral amyloid angiopathy in aged dogs and nonhuman primates / Lary C. Walker 313

Chapter 20 Vascular transport of Alzheimer's amyloid [beta] peptides and apolipoproteins / Berislav V. Zlokovic, Jorge Ghiso, Blas Frangione 325.

Notes:

Includes index.

ISBN:

0792363663

OCLC:

44695196