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Genetic manipulation of receptor expression and function / edited by Domenico Accili.

Holman Biotech Commons QH603.C43 G47 2000
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Format:
Book
Contributor:
Accili, Domenico.
Series:
Receptor biochemistry and methodology
Receptor biochemistry and methodology series
Language:
English
Subjects (All):
Cell receptors.
Genetic engineering.
Gene targeting.
Cell receptors--Research--Methodology.
Cell Membrane.
Receptors, Cell Surface.
Genetic Engineering.
Gene Targeting.
Medical Subjects:
Cell Membrane.
Receptors, Cell Surface.
Genetic Engineering.
Gene Targeting.
Physical Description:
xii, 240 pages, 4 unnumbered pages of color plates : illustrations ; 26 cm.
Place of Publication:
New York : Wiley-Liss, [2000]
Summary:
Receptor biochemists, neuroscientists, molecular biologists, cell biologists, and molecular geneticists will find Genetic Manipulation of Receptor Expression and Function a useful guide.
Contents:
1. Transgenic Rescue of Mutant Phenotypes Using Large DNA Fragments / Sally A. Camper, Thomas L. Saunders 1
2. Behavioral Characterization of Transgenic and Knockout Mice / Jacqueline N. Crawley 23
3. Genetic Analysis of Receptor Phenotypes / Scott Bultman, Patricia Green, Terry Magnuson 39
4. Immortalization of Cell Lines From Transgenic and Knockout Mice by Viral Transformation / Janice Yang Chou 55
5. The VP 16-Dependent Binary System for Inducible Gene Expression in Transgenic Mice / Claudia Kappen 69
6. Gene-Targeting Strategies in the Analysis of Alcohol and Anesthetic Mechanisms / Gregg E. Homanics 93
7. In Vivo Functions of the c-Met Gene: (HGF/SF Receptor) / Silvia Giordano, Paolo M. Comoglio 111
8. Tissue-Specific Knockouts of Insulin Receptor Tyrosine Kinase / Rohit N. Kulkarni, M. Dodson Michael, C. Ronald Kahn 129
9. Targeted Dominant Negative Mutations / William J. LaRochelle, Giulia Celli, Glenn Merlino 155
10. Toxin-Mediated Targeted Cell Ablation In Vivo / John Drago, John Y.F. Wong 175
11. Antisense RNA-Mediated Inhibition of Gene Expression / Hsien-yu Wang, Christopher M. Moxham, Craig C. Malbon 189
12. Delivery of Antisense Oligonucleotides to the Brain to Analyze Receptor Function / Simranjit Kaur, Ian Creese 205.
Notes:
Includes bibliographical references and index.
ISBN:
0471350575
0471350567
OCLC:
42619527

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