Control of breathing in health and disease / edited by Murray D. Altose, Yoshikazu Kawakami.

Format:

Book

Contributor:

Altose, Murray D.

Kawakami, Yoshikazu, 1936-

Series:

Lung biology in health and disease ; v. 135.

Lung biology in health and disease ; v. 135

Language:

English

Subjects (All):

Respiratory organs--Diseases.

Respiration--Regulation.

Respiratory Physiological Phenomena.

Respiratory Function Tests.

Respiratory Tract Diseases--diagnosis.

Respiratory Tract Diseases--physiopathology.

Medical Subjects:

Respiratory Physiological Phenomena.

Respiratory Function Tests.

Respiratory Tract Diseases--diagnosis.

Respiratory Tract Diseases--physiopathology.

Physical Description:

xvii, 767 pages : illustrations ; 24 cm.

Place of Publication:

New York : Marcel Dekker, [1999]

Contents:

Introduction: Claude Lenfant iii

Part 1 Physiological Foundations

1. Central Neural Control of Breathing / John E. Remmers 1

II. Breathing and Central Pattern Generators 3

III. Rhythm Generators: Pacemaker or Network Mechanisms? 5

IV. Gasping and Eupnea: Two Types of Respiratory Rhythms in Adult Mammals 11

V. Ontological Considerations 15

VI. Lessons from Amphibia and Reptiles 18

VII. Central Neuronal Elements Generating and Controlling the Motor Output 25

VIII. Synaptic Connection 30

IX. Neurotransmitters and Neuromodulators 33

2. Chemical Control of Breathing / Yoshiyuki Honda, Hiroaki Tani 41

II. Carbon Dioxide Chemosensitivity 42

III. Hypoxic Chemosensitivity 51

3. Nonchemical and Behavioral Effects on Breathing / Ikuo Homma, Yuri Masaoka 89

II. Motor Pathways 90

III. Afferent Mechanisms 93

IV. Respiratory Sensation and Behavioral Control of Breathing 95

V. Posture and Breathing 97

VI. Emotions, Personality, and Breathing 99

4. Dyspnea and the Control of Breathing / Harold L. Manning, Richard M. Schwartzstein 105

II. Measurement of Dyspnea 106

III. Mechanisms of Dyspnea 109

IV. Relationship Between Respiratory Control and Respiratory Sensation 118

V. Interplay Between Breathing Pattern and Respiratory Sensation 120

VI. Dyspnea in Patients 122

5. Control of Breathing During Exercise / Kieran J. Killian, Norman L. Jones, E. J. Moran Campbell 137

II. Integrative Model 138

III. Exercise Task 139

IV. Metabolic Demand 139

V. The Respiratory Muscles in Exercise 143

VI. Control of Breathing During Exercise 149

VII. Sensory Aspects of Breathing During Exercise 154

6. Respiration and the Human Upper Airway / David P. White 163

II. Biomechanical Properties of the Human Upper Airway 164

III. The Nose 169

IV. The Pharynx 176

V. The Larynx 188

7. Periodic Breathing and Central Apnea / Michael C. K. Khoo 203

II. Periodic Breathing as an Instability in Control 205

III. Sleep

Wake State and Respiratory Stability 217

IV. Respiratory Pattern Generation and Periodic Breathing 227

V. Peripheral and Central Mechanisms Affecting Respiratory Stability 232

8. Clinical Assessment of the Respiratory Control System / Yasushi Akiyama, Yoshikazu Kawakami 251

II. Measurement of Respiratory Output 252

III. Methods of Evaluating Control of Breathing 257

IV. Behavioral Effects on Respiratory Test Results 279

Part 2 Clinical Aspects

9. Respiratory Control in Children: Clinical Aspects / Carol Lynn Rosen, Alia R. Bazzy-Asaad, Gabriel G. Haddad 289

I. Overview of Respiratory Control: A Conceptual Framework 289

II. Control of Respiration: Developmental Physiological Aspects 291

III. Clinical Disorders of Respiratory Control 294

IV. Assessment of Respiratory Control in Children 335

10. Ventilatory Control in the Elderly / David W. Hudgel 367

II. Control of Breathing in the Elderly 367

III. Ventilatory Variability in Aging 369

IV. Breathing During Exercise in the Elderly 370

V. Sleep Quality in the Elderly 371

VI. Sleep-Disordered Breathing in the Elderly 372

11. Control of Breathing During Sleep and Sleep-Disordered Breathing / James B. Skatrud, M. Safwan Badr, Barbara J. Morgan 379

II. Epidemiology of Sleep-Disordered Breathing 380

III. Determinants of Breathing Pattern Instability 381

IV. Determinants of Upper Airway Patency 389

V. High Upper Airway Resistance Syndromes 396

VI. Sleep Apnea Syndromes 400

VII. Treatment of Sleep-Disordered Breathing 405

12. Control of Breathing in Chronic Obstructive Pulmonary Disease / Neil S. Cherniack 423

II. Effects of COPD on Respiratory System Function 425

III. Compensatory Actions of the Control System in COPD 426

IV. Effect of COPD on Ventilation 428

V. Factors Limiting Load Compensation and Producing Hypercapnia 429

VI. Breathing Patterns and Hypercapnia in COPD 431

VII. Factors Modifying Respiratory Control System Operation 432

13. Control of Breathing in Interstitial Lung Disease / Anthony F. DiMarco 439

II. Pulmonary Mechanics 442

III. Breathing Pattern 443

IV. Respiratory Muscle Function 444

V. Respiratory Control Mechanisms 446

14. Control of Breathing in Acute Ventilatory Failure and During Mechanical Ventilation / Catherine S. H. Sassoon, Martin J. Tobin 469

II. Control of Breathing in Acute Ventilatory Failure 471

III. Control of Breathing During Mechanical Ventilation 489

15. Control of Breathing in Neuromuscular Disease / Peter Martin Anthony Calverley 517

II. Clinical Features 518

III. Ventilatory Control: Theory and Assessment 521

IV. Ventilatory Control in NMD During Wakefulness 525

V. Respiratory Control During Sleep 535

VI. Implications for Treatment 541

16. Control of Ventilation in Congestive Heart Failure / Steven M. Scharf, Harly E. Greenberg 551

II. Changes in Respiratory Mechanics in CHF 552

III. Pulmonary Afferent Reflexes: Overview 552

IV. Ventilatory Reflexes Elicited from the Pulmonary Vasculature 554

V. Mechanisms Underlying the Ventilatory Response to Exercise in CHF 557

VI. Control of Respiration During Sleep in CHF 563

17. Control of Breathing in Endocrine and Metabolic Disorders and in Obesity / John V. Weil, Clifford W. Zwillich 581

II. Thyroid Diseases 581

III. Diabetes 588

IV. Acromegaly 589

V. Sex Hormones 589

VI. Obesity 593

18. Control of Breathing Following Lung Transplantation in Humans / Mark Heims Sanders 609

II. Are the Lungs and Lower Airways Truly Denervated Following Lung Transplantation? 610

III. Effect of Lung Transplantation on the Defense of Ventilation with Changing Resting Lung Volume 612

IV. The Effect of Lung Transplantation on Breathing During Wakefulness and Sleep 614

V. The Effect of Lung Transplantation on Ventilatory Chemoresponsiveness 617

VI. The Effect of Lung Transplantation on Perception of Breathing and Breath-Holding 622

VII. The Effect of Lung Transplantation on Exercise 624

19. The Hyperventilation Syndrome / Hans Folgering 633

II. Signs and Symptoms 636

III. Pathophysiology of the Control of Breathing 641

IV. Diagnosis 647

V. Therapy 652

20. Management of Respiratory Insufficiency / Murray D. Altose 661

II. Respiratory Control System 662

III. Causes of Respiratory Insufficiency 662

IV. Management Approaches 667.

Notes:

Includes bibliographical references and index.

ISBN:

0824798546

OCLC:

41528654