The comprehensive sourcebook of bacterial protein toxins / editors, Joseph E. Alouf and John H. Freer.

Format:

Book

Contributor:

Freer, J. H. (John H.)

Alouf, J. E. (Joseph E.)

Rosengarten Family Fund.

Language:

English

Subjects (All):

Bacterial toxins.

Physical Description:

xv, 718 pages, 4 unnumbered pages of plates : illustrations (some color) ; 29 cm

Edition:

Second edition.

Other Title:

Bacterial protein toxins

Place of Publication:

London ; San Diego, Calif. : Academic Press, [1999]

Summary:

The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the First Edition, with 70% totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete overview of the field.

Contents:

Introductory Section

1. Plasmids, phages and pathogenicity islands: lesson on the evolution of bacterial toxins / Ulrich Dobrindt, Jorg Hacker 3

Section I Toxins Acting on Cytosolic Targets

2. The Ras superfamily of small GTP-binding proteins as targets for bacterial toxins / Patrice Boquet 27

3. Molecular, functional and evolutionary aspects of ADP-ribosylating toxins / Mariagrazia Pizza, Vega Masignani, Rino Rappuoli 45

4. Binding, uptake, routing and translocation of toxins with intracellular sites of action / Sjur Olsnes, Jorgen Wesche, Pal O. Falnes 73

5. Regulation of diphtheria toxin production: characterization of the role of iron and the diphtheria toxin repressor / Joanne Goranson-Siekierke, Randall K. Holmes 94

6. Cholera toxin and Escherichia coli heat-labile enterotoxin / Timothy R. Hirst 104

7. Bordetella pertussis protein toxins / Camille Locht, Rudy Antoine 130

8. Clostridial toxins acting on the cytoskeleton / Monica Thelestam, Esteban Chaves-Olarte, Michael Moos, Christoph von Eichel-Streiber 147

9. Structural and genomic features of clostridial neurotoxins / Michel R. Popoff, Jean-Christophe Marvaud 174

10. Pathophysiological properties of clostridial neurotoxins / Judit Herreros, Giovanna Lalli, Cesare Montecucco, Giampietro Schiavo 202

11. The family of Shiga toxins / David W.K. Acheson, Gerald T. Keusch 229

12. The bifactorial Bacillus anthracis lethal and oedema toxins / Stephen A. Leppla 243

13. Helicobacter pylori vacuolating cytotoxin and associated pathogenic factors / Cesare Montecucco, Emanuele Papini, Marina de Bernard, John L. Telford, Rino Rappuoli 264

Section II Membrane-Damaging Toxins

14. Biophysical methods and model membranes for the study of bacterial pore-forming toxins / Gianfranco Menestrina, Beatrix Vecsey Semjen 287

15. Membrane-damaging and cytotoxic phospholipases / Richard W. Titball 310

16. The family of the multigenic encoded RTX toxins / Albrecht Ludwig, Werner Goebel 330

17. The family of Serratia and Proteus cytolysins / Volkmar Braun, Ralf Hertle 349

18. The channel-forming toxin aerolysin / J. Thomas Buckley 362

19. Haemolysins of Vibrio cholerae and other Vibrio species / Sumio Shinoda 373

20. [delta]-Toxin, related haemolytic toxins and peptidic analogues / Jean Dufourcq, Sabine Castano, Jean-Claude Talbot 386

21. The bi-component staphylococcal leucocidins and [gamma]-haemolysins (toxins) / Gilles Prevost 402

22. Enterococcus faecalis cytolysin and Bacillus cereus bi- and tri-component haemolysins / Michael S. Gilmore, Michelle C. Callegan, Bradley D. Jett 419

23. Clostridium septicum pore-forming and lethal [alpha]-toxin / Rodney K. Tweten, Bret R. Sellman 435

24. Introduction to the family of the structurally related cholesterol-binding cytolysins ('sulfhydryl-activated' toxins) / Joseph E. Alouf 443

25. Streptolysin O / Joseph E. Alouf, Michael Palmer 457

26. Pneumolysin: structure, function and role in disease / Timothy J. Mitchell 476

27. Perfringolysin O / Jamie Rossjohn, Rodney K. Tweten, Julian I. Rood, Michael W. Parker 490

28. Listeriolysin, the thiol-activated haemolysin of Listeria monocytogenes / Thomas Jacobs, Ayub Darji, Siegfried Weiss, Trinad Chakraborty 511

Section III Other Toxins of Clinical, Pharmacological, Immunological and Therapeutic Interest

29. Enterotoxigenic Escherichia coli heat-stable toxins / J. Daniel Dubreuil 525

30. Heat-stable enterotoxins of Vibrio and Yersinia species / Tae Takeda, Ken-ichi Yoshino, Thandavarayan Ramamurthy, G. Balakrish Nair 545

31. Bacteroides fragilis toxins / Cynthia L. Sears 557

32. Superantigenic Streptococcus pyogenes erythrogenic/pyrogenic exotoxins / Joseph E. Alouf, Heide Muller-Alouf, Werner Kohler 567

33. Properties of Staphylococcus aureus enterotoxins and toxic shock syndrome toxin-1 / Steven R. Monday, Gregory A. Bohach 589

34. Yersinia pseudotuberculosis superantigenic toxins / Christophe Carnoy, Michel Simonet 611

35. The pathogenesis of shock and tissue injury in Clostridia gas gangrene / Dennis L. Stevens, Amy E. Bryant 623

36. Toxin-induced modulation of inflammatory processes / Brigitte Konig, Andreas Drynda, Andreas Ambrosch, Wolfgang Konig 637

37. Staphylococcal epidermolytic toxins: structure, biological and pathophysiological properties / Yves Piemont 657

38. Bacterial toxins as food poisons / Per Einar Granum, Sigrid Brynestad 669

39. Diphtheria toxin-based interleukin-2 fusion proteins / Johanna C. vanderSpek, John R. Murphy 682

40. Native and genetically engineered toxin-based vaccines for cholera and Escherichia coli diarrhoeas / Ann-Mari Svennerholm, Jan Holmgren 691.

Notes:

Rev. ed. of: Sourcebook of bacterial protein toxins.

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Rosengarten Family Fund.

ISBN:

0120530759

OCLC:

41465017