Toxicology in risk assessment / edited by Harry Salem and Eugene J. Olajos.

Format:

Book

Contributor:

Salem, Harry, 1929-

Olajos, Eugene J.

Language:

English

Subjects (All):

Health risk assessment--Congresses.

Health risk assessment.

Toxicology--Congresses.

Toxicology.

Hazardous Substances--toxicity.

Environmental Pollutants--toxicity.

Risk Assessment.

Medical Subjects:

Hazardous Substances--toxicity.

Environmental Pollutants--toxicity.

Risk Assessment.

Genre:

Conference papers and proceedings.

Physical Description:

xix, 313 pages : illustrations, maps ; 25 cm

Place of Publication:

Philadelphia : Taylor & Francis, [2000]

Summary:

Toxicology is an integral part of the risk assessment process. In this book, investigators from the scientific and regulatory communities describe recent technical developments in risk assessment embracing toxicology and its allied sciences, risk qualification and characterisation, risk management, and risk communication. Case studies pertaining to current issues involving chemical and environmental risks, including military and industrial scenarios, are presented. Chapters describe value and ethical choices underlying toxicological decisions, economic and legal implications of regulations, understanding risk, and recommendations of the commission on risk assessment and risk management.

Contents:

1 A Window of Opportunity for Toxicology / John Doull 1

2 The Evolving Principles of Risk Analysis / Margaret M. MacDonell, Kirpal S. Sidhu, Jasvinder S. Sidhu 7

3 How to Communicate Risk in a Low Trust / High Concern Environment / Keith A. Fulton 33

4 Values and Ethical Choices That Underlie Toxicologic and Risk-Analysis Decisions / C. Richard Cothern 39

5 Improving the Risk-Assessment Process / Leo G. Abood 47

6 Improving Risk Characterization at the U.S. Environmental Protection Agency / Edward V. Ohanian 51

7 Multiple Factors in Risk Assessment / Leo G. Abood 57

8 Environmental Factors Modifying Sensitivity to Chemicals / Bernard Weiss 65

9 Animal Model of Chemical Sensitivity Involving Cholinergic Agents / David H. Overstreet, Amir H. Rezvani, Ying Yang, Mani Hamedi, David S. Janowsky 75

10 Application of Chemical Hormesis Concept to Risk Assessment: Reproductive Toxicity as an Example / Edward J. Calabrese, Linda A. Baldwin 95

11 Trends in toxicology Modeling for Risk Assessment / Shayne C. Gad 107

12 Overview of Environmental Decision-Support Software / T. M. Sullivan, P. D. Moskowitz, M. Gitten 147

13 Application of Risk-Assessment Techniques to Military Deployments: Operation Desert Storm, Operation Joint Endeavor, Operation Desert Focus / Jack M. Heller 163

14 Application of Risk-Assessment Techniques to Military Scenarios: Multipathway Exposure Assessment for Chemical Agent Incinerators / Hsieng-Ye Chang 183

15 A Drinking Water Advisory: Consumer Acceptability Advice and Health Effects Analysis on Methyl Tertiary-Butyl Ether / Charles O. Abernathy, Julie T. Du, Amal Mahfouz, Maria M. Gomez-Taylor, Joyce M. Donohue 191

16 Arsenic: Moving Toward a Regulation / Charles O. Abernathy, Irene S. Dooley, James Taft, Jennifer Orme-Zavaleta 211

17 The Evolution of Health-Risk Assessment: Trichloroethylene as a Case Study / Elizabeth A. Maull, Harvey J. Clewell 223

18 History of Methylene Chloride in Consumer Products: Tracing Scientific Knowledge, Regulations, and Perceptions / Donna M. Riley, Paul S. Fischbeck 235

19 Risk Assessment and Risk Management in Regulatory Decision Making: Recommendations of the Commission on Risk Assessment and Risk Management / Gail Charnley, the Members of the Commission on Risk Assessment and Risk Management 261

20 Risk Assessment and Risk Management: Pathways Toward Process Enhancement / Eugene J. Olajos, Harry Salem 269.

Notes:

Includes bibliographical references and index.

ISBN:

1560328371

OCLC:

42366698