A practical guide to human cancer genetics / Shirley V. Hodgson and Eamonn R. Maher.

Format:

Book

Author/Creator:

Hodgson, S. V.

Contributor:

Maher, E. R.

Language:

English

Subjects (All):

Cancer--Genetic aspects.

Cancer.

Neoplasms--genetics.

Medical Subjects:

Neoplasms--genetics.

Local Subjects:

Cancer--Genetic aspects.

Physical Description:

xvii, 336 pages : illustrations ; 25 cm

Edition:

Second edition.

Other Title:

Human cancer genetics

Place of Publication:

Cambridge, England : Cambridge University Press, 1999.

Summary:

This extensively up-dated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics - an area that has made significant advances since publication of the first edition. The opening section presents the the principles of cancer genetics and introduces the basic concepts and mechanisms of tumourigenesis and inherited predisposition to cancer. The second part of the book provides information, on a systems basis, on the incidence, significance and management of predisposition to individual cancers. The final section then deals with specific inherited cancer syndromes, giving practical guidance on clinical investigation, screening and management of affected patients and relatives at risk. Up-to-date details of the genetic mapping of inherited cancer syndromes and the molecular genetic changes in individual cancers are also provided. Finally, an appendix provides a helpful revision guide to the fundamental principles of genetics. This practical and clear account will benefit clinicians and research workers in oncology, genetics, surgery and general medicine.

Notes:

Includes bibliographical references (pages 251-321) and index.

ISBN:

0521649617

0521640253

OCLC:

41670822