VIP, PACAP, and related peptides : third international symposium / edited by Wolf-Georg Forssmann, Sami I. Said.

Format:

Book

Conference/Event

Contributor:

Forssmann, W.-G. (Wolf-Georg), 1939-

Saʻīd, Sāmī.

Conference Name:

International Symposium on VIP, PACAP, and Related Peptides (3rd : 1997 : Freiburg, Germany)

Series:

Annals of the New York Academy of Sciences ; v. 865.

Annals of the New York Academy of Sciences ; v. 865

Language:

English

Subjects (All):

Peptide hormones--Physiological effect--Congresses.

Peptide hormones.

Vasoactive intestinal peptide--Physiological effect--Congresses.

Vasoactive intestinal peptide.

Adenylate cyclase--Agonists--Congresses.

Adenylate cyclase.

Pituitary hormones--Physiological effect--Congresses.

Pituitary hormones.

Neuropeptides.

Pituitary hormones--Physiological effect.

Circumcellions.

Peptide hormones--Physiological effect.

Vasoactive Intestinal Peptide.

Medical Subjects:

Neuropeptides.

Vasoactive Intestinal Peptide.

Genre:

Conference papers and proceedings.

Physical Description:

611 pages : illustrations (some color) ; 24 cm.

Place of Publication:

New York, N.Y. : New York Academy of Sciences, 1998.

Contents:

Part I. Regulation of Gene Expression and Processing of VIP-PACAP Peptides

Special Lecture: Signaling by the Cytokine Receptor Superfamily / J. N. Ihle, W. Thierfelder, S. Teglund, D. Stravapodis, D. Wang, J. Feng, E. Parganas 1

Cis-Regulatory Elements Controlling Basal and Inducible VIP Gene Transcription / S. H. Hahm, L. E. Eiden 10

p22/PACAP Response Gene 1 (PRG1): A Putative Target Gene for the Tumor Suppressor p53 / H. Schafer, A. Trauzold, T. Sebens, W. Deppert, U. R. Folsch, W. E. Schmidt 27

Solution Structure Comparison of the VIP/PACAP Family of Peptides by NMR Spectroscopy / V. Wray, K. Nokihara, S. Naruse 37

Cloning and Functional Characterization of PACAP-Specific Receptors in Zebrafish / Y. Wei, S.C. Martin, G. Heinrich, S. Mojsov 45

Part II. Biochemistry of VIP-PACAP-Related Peptide Receptors

Induction of Type I PACAP Receptor Expression by the New Zinc Finger Protein Zac1 and p53 / A. Hoffmann, E. Ciani, S. Houssami, P. Brabet, L. Journot, D. Spengler 49

Cloning and Functional Characterization of the Human VIP1/PACAP Receptor Promoter / A. Couvineau, J. J. Maoret, C. Rouyer-Fessard, I. Carrero, M. Laburthe 59

Desensitization of the Human Vasoactive Intestinal Peptide Receptor (hVIP[subscript 2]/PACAP R): Evidence for Agonist-Induced Receptor Phosphorylation and Internalization / T. P. McDonald, D. M. Dinnis, C. F. Morrison, A. J. Harmar 64

Rat Aortic Smooth-Muscle Cell Proliferation Is Bidirectionally Regulated in a Cell Cycle-Dependent Manner via PACAP/VIP Type 2 Receptor / A. Miyata, K. Sato, J. Hino, H. Tamakawa, H. Matsuo, K. Kangawa 73

Identification of Binding Domains of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) for its Type 1 Receptor by Photoaffinity Labeling / Y. J. Cao, E. Kojro, M. Jasionowski, L. Lankiewicz, Z. Grzonka, F. Fahrenholz 82

Part III. Signal Transduction and Intracellular Metabolism Induced by VIP and PACAP

The Neurotrophic Activity of PACAP on Rat Cerebellar Granule Cells Is Associated with Activation of the Protein Kinase A Pathway and c-fos Gene Expression / D. Vaudry, M. Basille, Y. Anouar, A. Fournier, H. Vaudry, B. J. Gonzalez 92

PACAP-38 Protects Cerebellar Granule Cells from Apoptosis / L. Journot, M. Villalba, J. Bockaert 100

PACAP Protects Hippocampal Neurons against Apoptosis: Involvement of JNK/SAPK Signaling Pathway / S. Shioda, H. Ozawa, K. Dohi, H. Mizushima, K. Matsumoto, S. Nakajo, A. Takaki, C. J. Zhou, Y. Nakai, A. Arimura 111

Stimulatory Transducing Systems in Pancreatic Islet Cells / S. Emami, K. Regnauld, N. Ferrand, A. Astesano, M. Pessah, H. Phan, C. Boissard, J.-M. Garel, G. Rosselin 118

Part IV. Physiology of Effector Mechanisms

Miniglucagon: A Local Regulator of Islet Physiology / S. Dalle, P. Blache, D. Le-Nguyen, L. Le Brigand, D. Bataille 132

Pituitary Adenylate Cyclase Activating Polypeptide Induces Degranulation of Rat Peritoneal Mast Cells via High-Affinity PACAP Receptor-Independent Activation of G Proteins / J. Seebeck, M. L. Kruse, A. Schmidt-Choudhury, W. E. Schmidt 141

The Pituitary Adenylate Cyclase Activating Polypeptide Type 1 Receptor (PAC[subscript 1]-R) Is Expressed on Gastric ECL Cells: Evidence by Immunocytochemistry and RT-PCR / N. Zeng, T. Kang, R. M. Lyu, H. Wong, Y. Wen, J. H. Walsh, G. Sachs, J. R. Pisegna 147

A Critical View of the Methods for Characterization of the VIP/PACAP Receptor Subclasses / P. Robberecht, M. Waelbroeck 157

Part V. Neurobiology of VIP-PACAP-Related Peptides

Mechanisms of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP)-Induced Depolarization of Sympathetic Superior Cervical Ganglion (SCG) Neurons / V. May, M. M. Beaudet, R. L. Parsons, J. C. Hardwick, E. A. Gauthier, P. J. Durda, K. M. Braas 164

Sympathetic Neurons of the Chick Embryo Are Rescued by PACAP from Apoptotic Death / A. R. Wakade, D. Leontiv 176

Differential Display PCR Reveals Induction of Immediate Early Genes by Vasoactive Intestinal Peptide in PC12 Cells / A. Eschelbach, A. Hunziker, L. Klimaschewski 181

Developmental Regulation of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) and Its Receptor 1 in Rat Brain: Function of PACAP as a Neurotrophic Factor / D. Lindholm, Y. Skoglosa, N. Takel 189

Pituitary Adenylate Cyclase Activating Peptide (PACAP) in the Retinohypothalamic Tract: A Daytime Regulator of the Biological Clock / J. Hannibal, J. M. Ding, D. Chen, J. Fahrenkrug, P. J. Larsen, M. U. Gillette, J. D. Mikkelsen 197

VIP Neurotrophism in the Central Nervous System: Multiple Effectors and Identification of a Femtomolar-Acting Neuroprotective Peptide / D. E. Brenneman, G. Glazner, J. M. Hill, J. Hauser, A. Davidson, I. Gozes 207

VIP and PACAP in the CNS: Regulators of Glial Energy Metabolism and Modulators of Glutamatergic Signaling / P. J. Magistretti, J.-R. Cardinaux, J.-L. Martin 213

Glutamate Toxicity in the Lung and Neuronal Cells: Prevention or Attenuation by VIP and PACAP / S. I. Said, K. Dickman, R. D. Dey, A. Bandyopadhyay, P. De Stefanis, S. Raza, H. Pakbaz, H. I. Berisha 226

Part VI. Pharmacology of VIP-PACAP Agonists and Antagonists

Autoantibody Catalysis: No Longer Hostage to Occam's Razor / S. Paul 238

Analogues of VIP, Helodermin, and PACAP Discriminate between Rat and Human VIP[subscript 1] and VIP[subscript 2] Receptors / P. Gourlet, A. Vandermeers, J. Van Rampelbergh, P. De Neef, J. Cnudde, M. Waelbroeck, P. Robberecht 247

Maxadilan Is a Specific Agonist and Its Deleted Peptide (M65) Is a Specific Antagonist for PACAP Type 1 Receptor / D. Uchida, I. Tatsuno, T. Tanaka, A. Hirai, Y. Saito, O. Moro, M. Tajima 253

Importance of Conserved Cysteines in the Extracellular Loops of Human PACAP/VIP[subscript 1] Receptor for Ligand Binding and Stimulation of cAMP Production / S. M. Knudsen, J. W. Tams, B. S. Wulff, J. Fahrenkrug 259

Multiple Actions of a Hybrid PACAP Antagonist: Neuronal Cell Killing and Inhibition of Sperm Motility / I. Gozes, O. Perl, R. Zamostiano, S. Rubinraut, M. Fridkin, L. Shochat, L. M. Lewin 266

Special Lecture: The PACAP Ligand/Receptor System Regulates Cerebral Cortical Neurogenesis / E. Dicicco-Bloom, N. Lu, J. E. Pintar, J. Zhang 274

Part VII. Progress in Clinical Research of VIP-PACAP Peptides

VIP and Breast Cancer / T. W. Moody, J. Leyton, I. Gozes, L. Lang, W. C. Eckelman 290

Coordinated Role of Vasoactive Intestinal Peptide and Nitric Oxide in Cardioprotection / D. K. Das, R. Kalfin, N. Maulik, R. M. Engelman 297

The Protective Effect of Vasoactive Intestinal Peptide (VIP) on Stress-Induced Gastric Ulceration in Rats / N. Tuncel, N. Erkasap, V. Sahinturk, D. Dogrukol Ak, M. Tuncel 309

Is There Appetite after GLP-1 and PACAP? / J. Christophe 323

On the Treatment of Diabetes Mellitus with Glucagon-like Peptide-1 / J. J. Holst, C. Deacon, M. B. Toft-Nielsen, L. Bjerre-Knudsen 336

Binding Sites for VIP in the Reorganizing Mucosa of the Irradiated Bowel / U. Hockerfelt, M. Hansson, S. Gulbenkian, L. Franzen, R. Henriksson, S. Forsgren 344

Main Sensory Neuropeptides, but not VIP and NPY, Are Involved in Bone Remodeling during Orthodontic Tooth Movement in the Rat / L. I. Norevall, L. Matsson, S. Forsgren 353

Special Lecture: PACAP[subscript 27] and Other Neuropeptides in the Inferior Mesenteric Ganglion / L. G. Ermilov, J. H. Szurszewski 360

Regulation of Gene Expression and Processing of VIP-PACAP Peptides

Induction of Multiple Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Transcripts through Alternative Cleavage and Polyadenylation of proPACAP Precursor mRNA / S. A. Harakall, C. A. Brandenburg, G. A. Gilmartin, V. May, K. M. Braas 367

Biochemistry of VIP-PACAP-Related Peptide Receptors

A Model of the Receptors in the VIP Receptor Family / J. W. Tams, S. M. Knudsen, J. Fahrenkrug 375

Site-Directed Mutagenesis of Human VIP1 versus VIP2 Receptors / P. Nicole, K. Du, A. Couvineau, M. Laburthe 378

Constitutive Activation of the Human VIP1 Receptor / P. Gaudin, C. Rouyer-Fessard, A. Couvineau, J. J. Maoret, M. Laburthe 382

Construction of Chimeras between Human VIP1 and Secretin Receptors: Identification of Receptor Domains Involved in Selectivity towards VIP, Secretin, and PACAP / K. Du, P. Nicole, A. Couvineau, M.

Laburthe 386

Involvement of a Pit-1 Binding Site in the Regulation of the Rat Somatostatin Receptor 1 Gene Expression / H. Baumeister, W. Meyerhof 390

Relaxant Responses of VIP and PACAP in Rat Ileum: Receptors and Adaptive Supersensitivity / E. Ekblad, M. Ekelund, F. Sundler 393

VIP[subscript 1] and VIP[subscript 2] Receptors but not PVR1 Mediate the Effect of VIP/PACAP on Cytokine Production in T Lymphocytes / X. Jiang, H. Y. Wang, J. Yu, D. Ganea 397

Distribution and Ultrastructural Localization of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) and Its Receptor in the Rat Retina / T. Seki, S. Shioda, Y. Nakai, A. Arimura, R. Koide 408

Autoradiographic Visualization of the Receptor Subclasses for Vasoactive Intestinal Polypeptide (VIP) in Rat Brain / P. Vertongen, S. N. Schiffmann, P. Gourlet, P. Robberecht 412

Pituitary Adenylate Cyclase-Activating Polypeptide Receptors in the Fetal Human Adrenal Gland / L. Yon, L. Breault, V. Contesse, G. Bellancourt, C. Delarue, A. Fournier, J. G. Lechoux, N. Gallo-Payet, H. Vaudry 416

Neuropeptides in Developmental Tumors of the Central and Peripheral Nervous System / M. C. Fruhwald, M. S. O'Dorisio, S. L. Cottingham, S. J. Qualman, T. M. O'Dorisio 420

Signal Transduction and Intracellular Metabolism Induced by VIP and PACAP

PACAP Increases Cytosolic Calcium in Vasopressin Neurons: Synergism with Noradrenaline / S. Shioda, T. Yada, S. Nakajo, Y. Nakai, A. Arimura 427

Effect of PACAP-27 on Adenylate Cyclase in Ductal and Acinar Cells of Rat Submandibular Gland / E. Kabre, N. Chaib, H. Amsallem, A. Moran, M. C. Vandermeers, J. P. Dehaye 431

Distribution and Ultrastructural Localization of PACAP Receptors in the Rat Pancreatic Islets / M. Muroi, S. Shioda, T. Yada, C. J. Zhou, Y. Nakai, S. Nakaja, A. Arimura 438

Protein Kinase A Inhibition and PACAP-Induced Insulin Secretion in HIT-T15 Cells / K. Filipsson, B. Ahren 441

Physiology of Effector Mechanisms

PACAP and GLP-1 Protect Islet [beta]-Cells against Ca[superscript 2+] Toxicity Induced by High K[superscript +] / K. Yaekura, K. Yanagida, T. Yada 445

Autocrine Action of PACAP in Islets Augments Glucose-Induced Insulin Secretion / T. Yada, M. Sakurada, M. Nakata, S. Shioda, K. Yaekura, M. Kikuchi 451

A Target Cell to Oxyntomodulin and Glicentin: The Antral Smooth Muscle Cell / G. Rodier, R. Magous, T. Mochizuki, J. P. Bali, D. Bataille, C. Jarrousse 458

Effects of PACAP/VIP/Secretin on Pancreatic and Gastrointestinal Blood Flow in Conscious Dogs / S. Naruse, O. Ito, M. Kitagawa, H. Ishiguro, M. Nakajima, T. Hayakawa 463

Pituitary Adenylate Cyclase Activating Polypeptide Stimulates Insulin Secretion in a Glucose-Dependent Manner In Vivo / B. Ahren, K. Filipsson 466

Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) on cAMP Formation and Growth Hormone Release from Chicken Anterior Pituitary Cells / K. Peeters, L. Langouche, F. Vandesande, V. M. Darras, L. R. Berghman 471

Localization of Pituitary Adenylate Cyclase-Activating Polypeptide in the Central Nervous System of the European Eel Anguilla anguilla: Stimulatory Effect of PACAP on GH Secretion / M. Montero, L. Yon, K. Rousseau, A. Arimura, A. Fournier, S. Dufour, H. Vaudry 475

Effect of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) on Tyrosine Hydroxylase Gene Expression in the Rat Adrenal Medulla / M. Hong, L. Yon, A. Fournier, H. Vaudry, G. Pelletier 478

The Stimulatory Effect of VIP and PACAP on Adrenal Aldosterone Release / M. Radzikowska, E. Wasilewska-Dziubinska, B. Baranowska 482

Evidence for PACAP To Be an Autocrine Factor on Gonadotrope Cells / A. Radleff-Schlimme, S. Leonhardt, W. Wuttke, H. Jarry 486

Peptidergic Component of Non-Adrenergic Non-Cholinergic Relaxation of the Rat Gastric Fundus / D. Curro, P. Preziosi 492

Effect of VIP and PACAP on Vascular and Luminal Release of Serotonin from Isolated Perfused Rat Duodenum / M. Fujimiya, H. Yamamoto, A. Kuwahara 495

Sites of Actions of Contractile and Relaxant Effects of Pituitary Adenylate Cyclase Activating Peptide (PACAP) in the Internal Anal Sphincter Smooth Muscle / S. Rattan, S. Chakder 503

PACAP Inhibits Spontaneous Contractions in the Intestine of the Atlantic Cod, Gadus morhua / C. Olsson, S. Holmgren 512

Effect of Sodium Depletion by Frusemide on Tissue Concentrations and Metabolism of VIP / K. A. Duggan, V. Z. C. Ye 515

Neurobiology of VIP-PACAP-Related Peptides

Neuromodulator Role of VIP in Recovery of Rat Behavior and Brain Neurotransmitter Levels after Frontal Lobectomy / M. Karganov, G. Romanova, W. Braslawsky, D. Tarshitz, G. Telegdy 519

Immunohistochemical Evidence for PACAP and VIP Interaction with Met-Enkephalin and CRF Containing Neurons in the Bed Nucleus of the Stria Terminalis / T. Kozicz, S. Vigh, A. Arimura 523

Distribution and Somatotopical Localization of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) in the Trigeminal Ganglion of Cats and Rats / M. Kausz, A. Arimura, K. Koves 529

Prenatal Expression of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) in Autonomic and Sensory Ganglia and Spinal Cord of Rat Embryos / H. S. Nielsen, J. Hannibal, J. Fahrenkrug 533

VIP and NPY Expression during Differentiation of Cholinergic and Noradrenergic Sympathetic Neurons / B. Schutz, M. K. H. Schafer, L. E. Eiden, E. Weihe 537

PACAP in Visceral Afferent Nerves Supplying the Rat Digestive and Urinary Tracts / J. Fahrenkrug, J. Hannibal 542

Pharmacology of VIP-PACAP Agonists and Antagonists

Galanin Controls Excitability of the Brain / S. A. Chepurnov, N.E. Chepurnova, R. K. Berdiev 547

Vasoactive Intestinal Peptide Supports Spontaneous and Induced Migration of Human Keratinocytes and the Colonization of an Artificial Polyurethane Matrix / U. Wollina 551

The Stimulatory Effect of VIP on Progesterone Release in Rats after Adrenalectomy, Ovariectomy, and Hysterectomy: Influence of VIP and PACAP38 on Progesterone Release in Rats after Ovariectomy and Hysterectomy / E. Wasilewska-Dziubinska, M. Radzikowska, B. Baranowska 556

Characterization of a PACAP-like Immunoreactive Component in Red Ginseng Root / N. Takashima, Y. Arakawa, K. Kataoka, N. Kurokawa, C. Yanaihara, N. Yanaihara 561

The Effect of Vasoactive Intestinal Polypeptide and Pituitary Adenylate Cyclase Activating Polypeptide on Tolerance to Morphine and Alcohol in Mice / G. Szabo, M. Macsai, E. Schek, G. Telegdy 566

The Effect of Vasoactive Intestinal Peptide (VIP) and Inhibition of Nitric Oxide on Renal Tissue Injury of Rats Exposed to Hemorrhagic Ischemia and Retransfusion: A Possible Interaction Mechanism among Mast Cells and Tissue Histamine / S. H. Erden, N. Tuncel, Y. Aydin, V. Sahinturk, M. Kosar, M. Tuncel 570

Enhancement of Systemic and Pulmonary Vasoconstriction by [beta]-Amyloid Peptides and Its Suppression by Vasoactive Intestinal Peptide / S. I. Said, S. Raza, H. I. Berisha 582

Progress in Clinical Research of VIP-PACAP Peptides

The Effect of Vasoactive Intestinal Peptide (VIP) and Inhibition of Nitric Oxide Synthase on Survival Rate in Rats Exposed to Endotoxin Shock / N. Tuncel, F. C. Tore 586

Role of PACAP in the Regulation of Gonadotroph Hormone Secretion during Ontogenesis: A Single Neonatal Injection of PACAP Delays Puberty and Its Intracerebroventricular Administration before the Critical Period of Proestrous Stage Blocks Ovulation in Adulthood / K. Koves, J. Molnar, O. Kantor, A. Lakatos, K. Fogel, M. Kausz, M.C. Vandermeers-Piert, A. Somogyvari-Vigh, A. Arimura 590

Is an Intravenous Bolus Injection Required prior to Initiating Slow Intravenous Infusion of PACAP38 for Prevention of Neuronal Death Induced by Global Ischemia?: The Possible Presence of a Binding Protein for PACAP38 in Blood / A. Somogyvari-Vigh, J. Svoboda-Teet, S. Vigh, A. Arimura 595

Effect of Rat Glicentin on Intestinal Adaptation in Small Intestine-Resected Rats / Y. Hirotani, M. Taki, K. Kataoka, N. Kurokawa, T. Satoh, K. Sasaki, C. Yanaihara, W. Q. Luo, N. Yanaihara 601.

Notes:

"The papers in this volume resulted from a conference entitled 3rd International Symposium on VIP, PACAP, and Related Peptides, held September 17-10, 1997, in Freiburg, Germany"--Contents p.

Includes bibliographical references and index.

ISBN:

1573311537

1573311545

OCLC:

39786299