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Transcription factors and human disease / Gregg L. Semenza.
Holman Biotech Commons RB155.5 .S44 1999
Available
- Format:
- Book
- Author/Creator:
- Semenza, Gregg L.
- Series:
- Oxford monographs on medical genetics ; no. 37.
- Oxford monographs on medical genetics ; no. 37
- Language:
- English
- Subjects (All):
- Transcription factors--Pathophysiology.
- Genetic disorders--Pathophysiology.
- Carcinogenesis.
- Oncogenes.
- Genetic Diseases, Inborn--genetics.
- Transcription Factors.
- Neoplasms--genetics.
- Mutation--genetics.
- Transcription, Genetic.
- Genetic disorders.
- Physiology, Pathological.
- Transcription factors.
- Medical Subjects:
- Genetic Diseases, Inborn--genetics.
- Transcription Factors.
- Neoplasms--genetics.
- Mutation--genetics.
- Transcription, Genetic.
- Physical Description:
- xiii, 368 pages : illustrations ; 25 cm.
- Place of Publication:
- New York : Oxford University Press, [1999]
- Contents:
- Part I Transcriptional Regulation
- 1. Gene Expression and Transcriptional Regulation 3
- 2. Cis-acting Transcriptional Regulatory Elements 26
- 3. Trans-acting Factors 42
- Part II Transcriptional Pathophysiology
- 4. Mutations in Cis-acting Transcriptional Regulatory Elements 113
- 5. Mutations in Genes Encoding Transcription Factors: The Nuclear Receptor Superfamily 127
- 6. Other Zinc Finger Proteins: WT1 and GLI3 155
- 7. PAX Proteins 169
- 8. bHLH Proteins 199
- 9. Homeodomain Proteins 212
- 10. HMG Domain Proteins 247
- 11. POU Domain Proteins 261
- 12. Other Transcription Factor Families 272
- 13. Coactivators 289
- 14. General Transcription Factors 299
- 15. Somatic Cell Genetic Disease: Cancer 310
- 16. Epigenetic Disease: Teratogenesis 347.
- Notes:
- Date on title page is 1998; copyright date is 1999.
- Includes bibliographical references and index.
- ISBN:
- 0195112393
- OCLC:
- 187474974
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