Cryptococcus neoformans / by Arturo Casadevall and John R. Perfect.

Format:

Book

Author/Creator:

Casadevall, Arturo, 1957-

Contributor:

Perfect, John R., 1949-

Language:

English

Subjects (All):

Torulosis.

Cryptococcus neoformans.

Cryptococcosis.

Medical Subjects:

Cryptococcosis.

Physical Description:

viii, 541 pages : illustrations (some color) ; 26 cm

Place of Publication:

Washington, D.C. : ASM Press, [1998]

Summary:

The dramatic increase in the incidence of Cryptococcus neoformans infections calls for an up-to-date look at its biology and pathogenesis. This major new book provides a comprehensive review of the ecology, epidemiology, pathogenic mechanisms, host immunity, clinical features and diagnostic conditions, and principles of treatment and prevention of this important fungal pathogen. The only recent monograph on the subject, Cryptococcus neoformans goes beyond textbook chapters and journal articles to provide the most comprehensive, current information on basic science and clinical information relating to this fungus. The authors, investigators who have direct experience with the subject matter, provide objective data as well as interpretations and opinions.

Cryptococcus neoformans, a model organism for the understanding of disseminated mycoses, has become a major concern facing infectious disease physicians and immunocompromised patients. Now this valuable resource provides both experienced investigators and those new to the field of medical mycology an opportunity to review the vast database of knowledge on this major worldwide pathogen.

Contents:

1. Introduction to the Pathogen 1

2. Taxonomy 29

3. Ecology of Cryptococcus neoformans 41

4. Biochemistry 71

5. Molecular Biology 115

6. Virulence Factors 145

7. Physical Defenses and Nonspecific Immunity 177

8. Specific Immunity and Cytokines 223

9. Tissue Responses and Special Topics in Immunity 271

10. Animal Models and Veterinary Aspects of Cryptococcosis 325

11. Epidemiology 351

12. Diagnosis and Laboratory Techniques 381

13. Human Cryptococcosis 407

14. Therapy of Cryptococcosis 457

15. Prevention of Human Infection 519.

Notes:

Includes bibliographical references and index.

ISBN:

1555811078

OCLC:

39313424