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A clinician's guide to chemotherapy pharmacokinetics and pharmacodynamics / editors, Louise B. Grochow, Matthew M. Ames.

Holman Biotech Commons RC271.C5 C554 1998
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Format:
Book
Contributor:
Grochow, Louise B.
Ames, Matthew M.
Patrick B. and Anne Gaydosh Hughes Memorial Book Fund.
Language:
English
Subjects (All):
Antineoplastic agents.
Antineoplastic agents--Toxicology.
Antineoplastic Agents--pharmacokinetics.
Antineoplastic Agents--pharmacology.
Medical Subjects:
Antineoplastic Agents--pharmacokinetics.
Antineoplastic Agents--pharmacology.
Physical Description:
xvi, 578 pages : illustrations ; 26 cm
Place of Publication:
Baltimore : Williams & Wilkins, [1998]
Contents:
Section I. Variations in Drug Disposition 1
1 Individualized Dosing of Cancer Drugs and the Role of Therapeutic Monitoring / Louise Grochow 3
2 Pharmacogenetics and Polymorphisms / Richard Weinshilboum 17
3 Relationship of Age to the Disposition and Effects of Anticancer Drugs / Louise Grochow, Sharyn Baker 35
4 Protein Binding: Assessment and Importance / Clinton Stewart 55
5 Pharmacokinetics of Drug Delivery to the Central Nervous System / Mahendra Patel, Susan Blaney, Frank M. Balis 67
Section II. Specific Drugs and Classes 91
6 Anthracyclines / Jacques Robert 93
7 Bleomycin / Robert T. Dorr 175
8 Busulfan / Moustapha Hassan 189
9 Cytosine Arabinoside and Cytidine Analogs / Vassilios I. Avramis 209
10 Oxazaphosphorines: Cyclophosphamide and Ifosfamide / G. P. Kaijser, Jos H. Beijnen 229
11 Epipodophyllotoxins / Howard L. McLeod, William E. Evans 259
12 Fluorinated Pyrimidines / Gerard Milano, Marie-Christine Etienne 289
13 Hydroxyurea / Peter R. Gwilt 301
14 Methotrexate and Other Antifolates / William Crom 311
15 Nitrosoureas / Roy Jones, S. M. Matthes, C. Dufton, E. J. Shpall, S. I. Bearman, M. Ross, P. Cagnoni 331
16 Cisplatin, Carboplatin, and Platinum Analogs / Pierre R. Canal 345
17 Paclitaxel and Docetaxel / Mary Relling, Daryl Sonnichsen 375
18 Procarbazine, Dacarbazine, Temozolamide / Brenda J. Foster 395
19 6-Mercaptopurine and 6-Thioguanine / Gary R. Erdmann 411
20 Thiotepa / Bjorn Hagen 427
21 Camptothecan Analogues: Topotecan and Irinotecan / Elora Gupta, Mark J. Ratain 435
22 Vinblastine, Vincristine, and Vinorelbine / Dominique Leveque, Francois Jehl, Henri Monteil 459
23 Mitomycin C, Nitrogen Mustard, Chlorambucil, and Melphalan / Jaap Verweij, J. H. M. Schellens 471
Section III. Pharmacokinetic and Pharmacodynamic Methodology 495
24 Assay Methodology / Joel M. Reid, Matthew M. Ames 497
25 Noncompartmental Pharmacokinetic Analysis / Dennis A. Noe 515
26 Population Approaches to Estimation / Nancy C. Sambol, Romain Sechaud 531.
Notes:
Includes bibliographical references and index.
Local Notes:
Acquired for the Penn Libraries with assistance from the Patrick B. and Anne Gaydosh Hughes Memorial Book Fund.
ISBN:
0683181114
OCLC:
37322859

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