Mosby's pharmacology in nursing / Leda M. McKenry, Evelyn Salerno.

Format:

Book

Author/Creator:

McKenry, Leda M.

Contributor:

Salerno, Evelyn.

Language:

English

Subjects (All):

Pharmacology.

Nursing.

Chemotherapy.

Medical Subjects:

Pharmacology.

Physical Description:

xx, 1180 pages : illustrations (some color) ; 28 cm + 1 computer disk (3 1/2 in.)

Edition:

Twentieth edition.

Other Title:

Pharmacology in nursing

Mosby's pharmacology in nursing disk.

Place of Publication:

St. Louis, Mo. : Mosby, [1998]

System Details:

System requirements for accompanying disk: Windows 3.1 or Windows 95.

Contents:

Unit 1 Principles of Pharmacology

1 Orientation to Pharmacology 1

Historical Trends 2

Names of Drugs 3

Sources of Drugs 4

Drug Classification 4

The Scope of Nursing Management of Drug Therapy 6

The Nursing Process and Drug Administration 7

Goals of this Text 7

2 Legal and Ethical Aspects of Medication Administration 10

United States Drug Legislation 11

Canadian Drug Legislation 15

Standardization of Drugs 18

International Drug Control 18

Investigational Drugs 19

Nurses and Drug Research 21

Nursing Legislation 22

Ethical Considerations 26

Nursing Practice 27

3 Principles of Drug Action 29

General Properties of Drugs 30

Mechanisms of Drug Action 30

Side/Adverse Drug Responses 42

Nursing Management of Drug Therapy 46

Unit 2 The Nursing Process and Pharmacology

4 Assessment, Nursing Diagnosis, and Planning 48

Assessment 49

Analysis of Data 58

Nursing Diagnosis/Collaborative Problem 59

Planning for Drug Therapy 63

5 Implementation and Evaluation 66

Implementation 67

Unit 3 Biopsychosocial Aspects of Pharmacology

6 Cultural and Psychologic Aspects of Drug Therapy 99

Cultural Influences on Health Care 102

Ethnic and Racial Differences in Drug Response 106

Psychologic Aspects 107

Self-Treatment 109

7 Maternal and Child Drug Therapy 114

Childbearing Clients 115

Pediatric Clients 119

8 Drug Therapy for the Elderly 131

Physiologic Changes of Aging 132

Alterations in Pharmacokinetics 134

Alterations in Pharmacodynamics 134

Ineffective Management of the Self-Medication Regimen 134

Medications in the Elderly 135

9 Substance Misuse and Abuse 140

Substance Abuse and Professionals 141

Drug Testing 141

Etiologic Factors 142

Pharmacologic Basis of Dependence and Tolerance 143

Pathophysiologic Changes 146

Cultural Aspects of Drug Abuse 146

Types of Drugs Most Commonly Abused 146

10 Client Education for Self-Administration of Medication 170

Assessment 171

Nursing Diagnoses Related to Self-Administration of Medications 174

Planning 177

Implementation 177

Evaluation 181

Documentation 181

Unit 4 Current Issues in Pharmacology

11 Over-the-counter (OTC) Medications 184

Difference Between a Prescription and Nonprescription Drug 185

Change of a Drug from Prescription to OTC Status 185

Drug Marketing 186

Consumer Education for Over-the-counter Drugs 186

Selected OTC Drug Categories 187

Antacids 192

Laxatives 193

12 Alternative and Complementary Pharmacology 208

Remedies that Might Help 210

Remedies that Might Harm 214

Consumer Education for Alternative/Complementary Remedies 216

Part II Clinical Concepts

Unit 5 Drugs Affecting the Central Nervous System

13 Overview of the Central Nervous System 219

Brain 220

Spinal Cord 221

Cell Types 222

Blood-Brain Barrier 223

CNS Functional Systems 224

Synaptic Transmission in the CNS 225

14 Analgesics 228

Fears or Myths that Interfere with Pain Management 229

Pain Components and Concepts 230

Analgesic Pharmacology 240

Opioid (Agonist) Analgesics 240

Opioid Antagonists 255

Opioid Agonist-Antagonist Agents 257

Nonopioid Analgesics 259

Nonsteroidal Antiinflammatory Drugs 260

Thromboxane (TXA[subscript 2]) 267

Other Drugs 267

15 Anesthetics 273

General Anesthesia 274

Mechanism of Action 274

Stages of General Anesthesia 274

Significant Drug Interactions 275

Special Anesthesia Considerations 276

Types of General Anesthetics 279

Preanesthetic Agents/Anesthetic Adjunctive Agents 287

Local Anesthesia 288

Surface or Topical Anesthesia 288

Local Anesthetics 288

Anesthesia by Injection 293

16 Antianxiety, Sedative, and Hypnotic Drugs 296

Physiology of Sleep 297

Pediatric Drug Use 298

Geriatric Drug Use 299

Barbiturates 310

Miscellaneous Sedatives and Hypnotics 314

17 Anticonvulsants 320

Classification of Seizures 321

Types of Epilepsy 321

Relationship of Age to Seizures 322

Anticonvulsant Therapy 322

Hydantoins 328

Barbiturates 331

Succinimides 334

Benzodiazepines 335

18 Central Nervous System Stimulants 345

Anorexiant Drugs 346

Amphetamines 349

Other Central Nervous System Stimulants 351

19 Psychotherapeutic Drugs 359

Central Nervous System and Emotions 360

Role of Drug Therapy in Psychiatry 360

Antipsychotic or Neuroleptic Agents 364

Antipsychotic Agents 365

Antidepressant Therapy 378

Antimanic Therapy 388

Unit 6 Drugs Affecting the Autonomic Nervous System

20 Overview of the Autonomic Nervous System 393

Reflex Control System 394

Nervous System Classification 394

Differences Between the Parasympathetic and Sympathetic Systems 395

Neurohumoral Transmission 395

21 Drugs Affecting the Parasympathetic Nervous System 403

Autonomic Drugs 404

Cholinergic Drugs 404

Cholinergic Blocking Drugs 408

Ganglionic Drugs 413

Ganglionic Stimulating Drugs 414

Ganglionic Blocking Drugs 418

22 Drugs Affecting the Sympathetic (Adrenergic) Nervous System 421

Adrenergic Blocking Drugs 441

23 Drugs for Specific CNS-Peripheral Dysfunctions 453

Parkinson's Disease 454

Myasthenia Gravis 464

Alzheimer's Disease 468

Skeletal Muscle Relaxants 470

Central-Acting Skeletal Muscle Relaxants 471

Unit 7 Drugs Affecting the Cardiovascular System

24 Overview of the Cardiovascular System 478

The Heart 479

Coronary Vascular Supply of the Heart 486

25 Cardiac Glycosides 489

Heart Failure 490

Digitalis Glycosides 492

26 Antidysrhythmics 504

Disorders in Cardiac Electrophysiology 505

Group I-A Drugs 507

Group I-B Drugs 512

Group I-C Drugs 515

Group I Drugs (A, B, C) 516

Group II Drugs 516

Group III Drugs 516

Group IV: Miscellaneous Drug Group 520

Unclassified Antiarrhythmic Agent 520

27 Antihypertensives 522

Definition of Hypertension 523

Classification of Hypertension 524

Physiologic Control of Blood Pressure 524

Antihypertensive Therapy 526

Diuretic Drugs 529

Adrenergic Inhibiting (Sympatholytic) Agents 529

Angiotensin-Converting Enzyme Inhibitors 540

Calcium Antagonists 542

Vasodilators 542

28 Calcium Channel Blockers 550

Action 551

Dosing of Specific Agents 553

29 Vasodilators and Antihemorrheologic Agents 557

Angina 558

Vasodilators 558

Peripheral Vascular Disease 562

Hemorrheology 564

Unit 8 Drugs Affecting the Blood

30 Overview of the Blood 566

Blood Volume 567

Blood Composition 567

Coagulation 569

Blood Types 570

31 Anticoagulants, Thrombolytics, and Blood Components 572

Anticoagulant Drugs 573

Thrombolytic Agents 583

Antihemophilic Agents 586

Antiplatelet Agents 588

Hemostatic Agents 589

Blood and Blood Components 592

32 Antihyperlipidemic Drugs 598

Hyperlipidemic Disorders 599

Bile Acid Sequestering Agents 602

Additional Antihyperlipidemic Agents 604

Reductase Inhibitors 608

Unit 9 Drugs Affecting the Urinary System

33 Overview of the Urinary System 611

Anatomy and Physiology of the Kidney 612

Physiologic Regulation by the Kidney 613

34 Diuretics 616

Proximal Tubule Diuretics 617

Diluting Segment Diuretics 619

Loop Diuretics 623

Distal Tubule Diuretics/Potassium-Sparing Diuretics 625

Osmotic Diuretics 626

Diuretic Combinations 627

35 Uricosuric Drugs 629

Gout 630

36 Drug Therapy for Renal System Dysfunction 637

Acute Versus Chronic Renal Failure 638

Signs and Symptoms of Renal Failure or Insufficiency 638

Measurement of Renal Function 638

Special Needs of the CRF Client 639

Selected Drug Modifications in Renal Failure 640

Unit 10 Drugs Affecting the Respiratory System

37 Overview of the Respiratory System 644

Respiratory Tract Secretions 645

Bronchial Smooth Muscle 646

Control of Respiration 646

38 Mucokinetic and Bronchodilator Drugs 648

Mucokinetic Drugs 649

Diluents 649

Aerosol Therapy 650

Mucolytic Drugs 651

Drugs that Antagonize Bronchial Secretions 653

Bronchodilator Drugs 653

Sympathomimetic Drugs 656

Xanthine Derivatives 662

Prophylactic Asthmatic Drugs 666

39 Oxygen and Miscellaneous Respiratory Agents 671

Drugs that Affect the Respiratory Center 672

Cough Suppressants 677

Histamine 678

Antihistamines 681

Serotonin 684

Antiserotonins 685

Unit 11 Drugs Affecting the Gastrointestinal System

40 Overview of the Gastrointestinal Tract 687

Mouth (Oral Cavity) 688

Pharynx 688

Esophagus 689

Stomach 689

Liver 690

Gallbladder 690

Pancreas 690

Small Intestine 690

Large Intestine 690

41 Drugs Affecting the Gastrointestinal Tract 692

Drugs Affecting the Upper Gastrointestinal Tract 693

Agents that Affect the Mouth 693

Drugs that Affect the Stomach 695

Drugs Affecting the Gallbladder 713

Agents Affecting the Lower Gastrointestinal Tract 715

Laxatives 716

Antidiarrheals 719

Unit 12 Drugs Affecting the Visual and Auditory Systems

42 Overview of the Eye 724

43 Ophthalmic Drugs 727

Antiglaucoma Agents 731

Mydriatic and Cycloplegic Agents 736

Antiinfective/Antiinflammatory Agents 739

Topical Anesthetic Agents 742

Other Ophthalmic Preparations 742

44 Overview of the Ear 746

Anatomy and Physiology 747

Common Ear Disorders 747

45 Drugs Affecting the Ear 749

Antibiotic Ear Preparations 750

Corticosteroid Ear Preparations 750

Other Otic Preparations 750

Drug-Induced Ototoxicity 751

Unit 13 Drugs Affecting the Endocrine System

46 Overview of the Endocrine System 753

Hormones 754

Pituitary Gland 755

Thyroid Gland 757

Parathyroid Glands 759

Adrenal Glands 760

Pancreas 760

47 Drugs Affecting the Pituitary 763

Anterior Pituitary Hormones 764

Posterior Pituitary Hormones 766

48 Drugs Affecting the Parathyroid and Thyroid 769

Parathyroid 770

Thyroid 772

49 Drugs Affecting the Adrenal Cortex 781

Glucocorticoids 782

Mineralocorticoids 788

Antiadrenals (Adrenal Steroid Inhibitors) 789

50 Drugs Affecting the Pancreas 793

Hyperglycemia 794

Insulin Preparations 795

Oral Hypoglycemic Agents 803

Hyperglycemic Agents 807

Unit 14 Drugs Affecting the Reproductive System

51 Overview of the Female and Male Reproductive Systems 811

Endocrine Glands 812

Pituitary Gonadotropic Hormones 812

Female Reproductive System 812

Male Reproductive System 816

52 Drugs Affecting the Female Reproductive System 818

Gonadotropin-Releasing Hormone (GnRH) 819

Gonadotropin-Releasing Hormone Agonist 819

Nonpituitary Chorionic Gonadotropin 820

Menotropins 821

Female Sex Hormones 822

Oral Contraceptives 826

Ovulatory Stimulants and Drugs Used for Infertility 831

53 Drugs for Labor and Delivery 835

Drugs Affecting the Uterus 836

Lactation Inhibitors 841

54 Drugs Affecting the Male Reproductive System 843

Testosterone 844

Benign Prostatic Hyperplasia 846

55 Drugs Affecting Sexual Behavior 848

Drugs that Impair Libido and Sexual Gratification 849

Drugs that Enhance Libido and Sexual Gratification 851

The Nurse's Role in Human Sexuality 852

Unit 15 Drugs Used in Neoplastic Diseases

56 Antineoplastic Chemotherapy 854

Cell Kinetics 855

Principles of Chemotherapy 857

Combination Chemotherapy 857

Toxic Effects 858

Age-Related Considerations 858

57 Antineoplastic Agents 865

Antimetabolite Drugs 868

Alkylating Drugs 874

Nitrosureas 878

Alkylator-like Drugs 878

Antibiotic Antitumor Drugs 879

Mitotic Inhibitors 880

Miscellaneous Antineoplastic Agents 882

Cancer Chemotherapy Research 885

Unit 16 Drugs Used in Infectious Diseases and Inflammation

58 Overview of Infections, Inflammation, and Fever 888

Infections 888

Inflammation 890

Fever 891

Antimicrobial Therapy 892

59 Antibiotics 900

Penicillins and Related Antibiotics 902

Cephalosporins and Related Products 908

Macrolide Antibiotics 911

Lincomycins 912

Aminoglycosides 914

Tetracyclines 916

Chloramphenicol (Chloromycetin) 917

Fluoroquinolones 919

Miscellaneous Antibiotics 920

Urinary Tract Antimicrobials 922

Sulfonamides 924

Urinary Tract Antiseptics 926

Aztreonam and the Fluoroquinolones 928

Urinary Tract Analgesic 928

60 Antifungal and Antiviral Drugs 930

Antifungal Drugs 931

Antiviral Drugs 937

61 Other Antimicrobial Drugs and Antiparasitic Drugs 950

Malaria 951

Tuberculosis 957

Amebiasis 967

Other Protozoan Diseases 969

Helminthiasis 969

Leprosy 975

Unit 17 Drugs Affecting the Immunologic System

62 Overview of the Immunologic System 978

The Immune System 979

Immunocompetent Cells 980

Antibodies 981

Immunity 981

63 Serums, Vaccines, and Other Immunizing Agents 984

Current Issues 987

Side Effects/Adverse Reactions 988

64 Immunosuppressants and Immunomodulators 997

Immunosuppressants 1000

Immunomodulating Agents 1005

Unit 18 Drugs Affecting the Integumentary System

65 Overview of the Integumentary System 1012

Structure of the Skin 1013

Functions of the Skin 1013

Appendages of the Skin 1014

66 Dermatologic Drugs 1015

Skin Disorders 1016

General Dermatologic Preparations 1021

Prophylactic Agents 1022

Therapeutic Agents 1024

67 Debriding Agents 1034

Pressure Sores 1035

Pharmacologic Management 1037

Unit 19 Intravenous and Nutritional Therapy

68 Vitamins and Minerals 1043

Vitamins 1044

Minerals 1055

69 Fluids and Electrolytes 1058

Fluids 1059

Electrolytes 1062

70 Enteral and Parenteral Nutrition 1072

Enteral Nutrition 1073

Parenteral Nutrition 1078

Unit 20 Miscellaneous Agents

71 Antiseptics, Disinfectants, and Sterilant Agents 1084

Medical and Surgical Asepsis 1085

Antiseptics and Disinfectants 1085

Sterilants 1094

72 Diagnostic Agents 1095

Radiopaque Agents for Visualizing Organ Structure 1096

Agents for Evaluating Organ Function 1098

Agents for Screening and Monitoring Disorders and Immune Status 1104

73 Poisons and Antidotes 1108

Detection of Poisons 1109

Poison Control Centers 1112

Classification of Action of Poisons 1112

Specific Poisons, Symptoms, and Suggested Emergency Treatment 1113

Prevention of Poisoning 1116

Antidotes 1116

Common Poisons 1117

A Sugar-Free Products 1121

B Alcohol-Free Products 1122

C Drugs That Cause Body Organ Damage 1123

D Food-Drug Interactions 1125

E Drugs That Change Urine or Stool Color 1126

F Time to Draw Blood for Specific Medications 1127

G Additional Drug Product Information 1128.

Notes:

Accompanied by a disk entitled: Mosby's pharmacology in nursing disk.

Supplemented by a booklet: Quick medication administration reference, by Judith Myers (3rd ed. c1998).

Includes bibliographical references and index.

ISBN:

0815145152

OCLC:

40517045