Principles of medicinal chemistry / [edited by] William O. Foye, Thomas L. Lemke, David A. Williams.

Format:

Book

Contributor:

Foye, William O.

Lemke, Thomas L.

Williams, David A., 1938-

Language:

English

Subjects (All):

Pharmaceutical chemistry.

Chemistry, Pharmaceutical.

Medical Subjects:

Chemistry, Pharmaceutical.

Physical Description:

xii, 995 pages : illustrations ; 29 cm

Edition:

Fourth edition.

Place of Publication:

Baltimore : Williams & Wilkins, [1995]

Contents:

2. Medicinals of Plant Origin: Historical Aspects / William O. Foye 7

3. Biopharmaceutical Properties of Drug Substances / Sunil S. Jambhekar 12

4. Structural Features and Pharmacologic Activity / Ian W. Mathison, William E. Solomons, Richard R. Tidwell 25

5. Theoretic Aspects of Drug Design / Michael S. Tute, Lemont B. Kier 50

6. Molecular Modeling / James G. Henkel, Eric M. Billings 58

7. Receptors and Drug Action / Timothy J. Maher 75

8. Drug Metabolism / David A. Williams 83

9. Volatile Anesthetics / Ronald L. Jacoby, Karl A. Nieforth 141

10. Central Nervous System Depressants: Sedative-Hypnotics / Julius A. Vida 154

11. Anticonvulsants / Julius A. Vida 182

12. Neuroleptics and Anxiolytic Agents / John L. Neumeyer, Raymond G. Booth 199

13. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonism Agents and Skeletal Muscle Relaxants / John L. Neumeyer, Raymond G. Booth 232

14. Analgesics / David S. Fries 247

15. Central Nervous System Stimulants / Karl A. Nieforth, Gerald Gianutsos 270

16. Local Anesthetics / Matthias C. Lu 305

17. Cholinergic Agonists, Acetylcholinesterase Inhibitors, and Cholinergic Antagonists / Danny L. Lattin 321

18. Adrenergic Drugs / Robert K. Griffith, Elizabeth A. Johnson 345

19. Cardic Agents: Cardiac Glycosides, Antianginals, and Antiarrhythmic Drugs / Ahmed S. Mehanna 366

20. Anticoagulants, Coagulants, and Plasma Extenders / Richard H. Hammer 388

21. Diuretics / Gary O. Rankin 405

22. Antiallergic and Antiulcer Drugs / Maria Di Bella, Daniela Braghiroli, Donald T. Witiak 416

23. Cholesterol, Adrenocorticoids, and Sex Hormones / Robert W. Brueggemeier, Duane D. Miller, Donald T. Witiak 444

24. Antilipidemic Drugs / Dennis R. Feller, Larry M. Hagerman, Howard A. I. Newman, Donald T. Witiak 499

25. Nonsteroidal Anti-inflammatory Drugs / Ronald F. Borne 535

26. Drugs Affecting Sugar Metabolism / Edmund J. Hengesh 581

27. Amino Acids, Peptides, and Proteins / Roy L. Kisliuk 601

28. Pharmaceutical Biotechnology / Robert D. Sindelar 622

29. Vitamins and Coenzymes / Raymond W. Doskotch, Robert W. Curley, Jr. 652

30. Thyroid Function and Thyroid Drugs / Alireza Banijamali 688

31. Metabolite Antagonism / Nitya Anand 705

32. Parasite Chemotherapy / William O. Foye 730

33. Antimycobacterial Agents / Thomas L. Lemke 747

34. Antibiotics and Antimicrobial Agents / Lester A. Mitscher 759

35. Antifungal Agents / Eugene D. Weinberg 803

36. Antiseptics and Disinfectants / Thomas L. Lemke 812

37. Cancer Chemotherapy / William O. Foye, Sisir K. Sengupta 822

38. Antiviral Agents / Manohar L. Sethi 846

39. Approaches to Anti-AIDS Agents / Prem Mohan 862

40. Hormone Antagonists / V. Craig Jordan 877

41. Photochemotherapy / Francesco Dall'Acqua, Giulio Jori 893

42. Pesticides / John L. Neumeyer, Raymond G. Booth 908

43. Agents for Organ Imaging / Raymond E. Counsell, Jamey P. Weichert 927

pK[subscript a] Values for Some Drugs and Miscellaneous Organic Acids and Bases

pH Values for Tissue Fluids / David A. Williams.

Notes:

"A Lea & Febiger book."

Includes bibliographical references and index.

ISBN:

0683033239

OCLC:

30892084