Molecular diversity and combinatorial chemistry : libraries and drug discovery / Irwin M. Chaiken, Kim D. Janda, [editors].

Format:

Book

Contributor:

Chaiken, Irwin M.

Janda, Kim D., 1957-

Cambridge Healthtech Institute.

Series:

Conference proceedings series (American Chemical Society)

Conference proceeding series

Language:

English

Subjects (All):

Combinatorial chemistry--Congresses.

Combinatorial chemistry.

Drugs--Design--Congresses.

Drugs.

Drugs--Design.

Genre:

Conference papers and proceedings.

Physical Description:

ix, 328 pages : illustrations (some color) ; 24 cm.

Place of Publication:

Washington, DC : American Chemical Society, [1996]

Summary:

Reports progress on chemical, enzymatic, phage, and cell-derived libraries. Discusses synergy between structure-based design and combinatorial libraries. Presents applications of combinatorial libraries to drug discovery and new synthetic catalysis. Reports library screening approaches, including the use of NMR. Presents recent advances in solid-phase organic synthesis, liquid-phase organic synthesis, and high-throughput combinatorial organic synthesis. Discusses automation of organic synthesis as well as new methodologies for monitoring solid-phase organic synthesis.

Notes:

Proceedings of two conferences sponsored by Cambridge Healthtech Institute held at the Hotel Del Coronado, in Coronado, California, January 28-February 2, 1996.

Includes bibliographical references and indexes.

ISBN:

0841234507

OCLC:

34742361