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Antiepileptic drugs : mechanisms of action / editors, Gilbert H. Glaser, J. Kiffin Penry, Dixon M. Woodbury ; National Institute of Neurological and Communicative Disorders and Stroke, Epilepsy Advisory Committee, Subcommittee on Basic Research.

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Format:
Book
Contributor:
Glaser, Gilbert H.
Penry, J. Kiffin, 1929-
Woodbury, Dixon M.
National Institute of Neurological and Communicative Disorders and Stroke. Epilepsy Advisory Committee. Subcommittee on Basic Research.
Series:
Advances in neurology ; v. 27.
Advances in neurology ; v. 27
Language:
English
Subjects (All):
Epilepsy--Chemotherapy--Congresses.
Epilepsy.
Anticonvulsants--Congresses.
Anticonvulsants.
Anticonvulsants--Physiological effect--Congresses.
Anticonvulsants--pharmacology.
Epilepsy--drug therapy.
Anticonvulsants--Physiological effect.
Epilepsy--Chemotherapy.
Medical Subjects:
Anticonvulsants--pharmacology.
Epilepsy--drug therapy.
Genre:
Congresses.
Conference papers and proceedings.
Physical Description:
xix, 728 pages : illustrations ; 26 cm.
Place of Publication:
New York : Raven Press, [1980]
Contents:
History of the antiepileptic drugs
Mechanisms of antiepileptic drug action: clinical indicators
Morphological correlates of epilepsy: cells in the cerebral cortex
Morphological correlates of epilepsy: cells in the hippocampus
Ionic conditions and membrane behavior
Brain synaptosomes in epilepsy: organization of ionic channels and the Na+-K+ pump
Principles of synaptic transmission
Influence of potassium and neuroglia in the generation of seizures and their treatment
Neuronal mechanisms of seizure inititation
Complex neuronal systems: approach to development of new strategies in the treatment of epilepsy
Drug transport into the central nervous system
Receptor modeling for anticonvulsant and convulsant drugs
stereochemical similarities in chemically different antiepileptic drugs
Quantitative structure-activity relationship studies of anticonvulsant drugs
Convulsant drugs: mechanisms of action
Phenytoin: introduction and history
Phenytoin: biopharmacology
Phenytoin: binding
Phenytoin: electrophysiological studies in simple neuronal systems
Phenytoin: blockage of resting sodium channels
Phenytoin: electrophysiological effects at the neuromuscular junction.
Phenytoin: biochemical membrane studies
Phenytoin: calcium- and calmodulin-dependent protein phosphorylation and neurotransmitter release
Phenytoin: relationship between cerebellar function and epileptic discharges
Phenytoin: cyclic nucleotide regulation in the brain
Phenytoin: relevant side effects
Phenytoin: proposed mechanisms of anticonvulsant action
Phenobarbital: introduction
Phenobarbital: biopharmacology
Phenobarbital: binding
Barbiturates: physiological effects I
Barbiturates: physiological effects II
Barbiturates: inhibition of sustained firing in Aplysia neurons
Phenobarbital: chemical-biophysical effects
Phenobarbital: proposed mechanisms of antiepileptic action
Carbamazepine
Oxazolidinediones
Succinimides
Benzodiazepines
Carbonic anhydrase inhibitors
Ketogenic diet: mechanism of anticonvulsant action
Sodium valproate
Hormones and epilepsy
Epilepsy and antiepileptic drugs: a speculative synthesis.
Notes:
Includes bibliographical references and index.
Other Format:
Online version: Antiepileptic drugs.
ISBN:
0890042519
9780890042519
OCLC:
5830104

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