The Lactoperoxidase system : chemistry and biological significance / edited by Kenneth M. Pruitt, Jorma Tenovuo.

Format:

Book

Contributor:

Pruitt, Kenneth M., 1933-

Tenovuo, Jorma, 1949-

Series:

Immunology series ; v. 27.

Immunology series ; v. 27

Language:

English

Subjects (All):

Peroxidase.

Immunity.

Saliva.

Peroxidases.

Saliva--enzymology.

Medical Subjects:

Peroxidases.

Saliva--enzymology.

Physical Description:

viii, 257 pages : illustrations ; 24 cm.

Place of Publication:

New York : M.Dekker, [1985]

Summary:

This important, new reference is the first single source devoted to the lactoperoxidase system, examining the full range of biochemical and biological aspects of this nonimmunoglobulin defense factor and reviewing the current status of potential clinical applications. Emphasizing the role of the various nonantibody defense systems in protection from viruses, bacteria, and other microorganisms, The Lactoperoxidase System covers the antimicrobial mechanisms of lactoperoxidase, offering varied perspectives regarding attempts to enhance the antimicrobial properties of peroxidase systems for therapeutic uses ... details the basic biochemistry of peroxidase-catalyzed oxidation and halogenation reactions, promoting understanding of the vital function of oxidative enzymes in protecting mucosal surfaces ... treats the problems of collection, treatment, and analysis of mammaliam exocrine secretions, helping improve laboratory techniques and data interpretation ... and includes more than 800 references, facilitating access to the widely scattered literature. Providing the insight and experience of 13 leading international researchers, The Lactoperoxidase System will be an invaluable reference for microbiologists, immunologists, and biochemists; dentists, oral pathologists, and oral biologists; veterinarians and dairy scientists; and medical and dental students. Moreover, the book is an ideal text on the subject for graduate-level courses in microbiology, immunology, and clinical dentistry.

Contents:

1. The Biological Significance of the Nonimmunoglobulin Defense Factors / Irwin D. Mandel, Solon A. Ellison 1

2. The Chemical Structure of Lactoperoxidase / Karl-Gustav Paul, Per-Ingvar Ohlsson 15

3. Products of Lactoperoxidase-Catalyzed Oxidation of Thiocyanate and Halides / Edwin L. Thomas 31

4. Steady-State Kinetics of Lactoperoxidase-Catalyzed Reactions / William G. Bardsley 55

5. Genetic Variation of Salivary Peroxidase / Edwin A. Azen 89

6. The Peroxidase System in Human Secretions / Jorma O. Tenovuo 101

7. The Lactoperoxidase System of Bovine Milk / Bruno Reiter 123

8. Biochemistry of Peroxidase System: Antimicrobial Effects / Kenneth M. Pruitt, Bruno Reiter 143

9. Bacterial Hydrogen Peroxide Production / Edwin L. Thomas 179

10. Effect of Sugars and Sugar Alcohols on Salivary Peroxidase / Kauko K. Makinen 203

11. Activation of the Salivary Peroxidase Antimicrobial System: Clinical Studies / Henk Hoogendoorn 217

12. Antibody Targeting of the Antimicrobial and Antitumor Activity of the Peroxidases / Roland R. Arnold 229.

Notes:

Includes bibliographical references and index.

ISBN:

0824772989

OCLC:

11518243